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Merck
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文件

C113080

Sigma-Aldrich

DMT-dC(ac)亚磷酰胺

configured for PerkinElmer, configured for Polygen

别名:

N-乙酰基-5′-O-[双（4-甲氧基苯基）苯基甲基] -2′-脱氧胞苷，3′-[2-氰基乙基N,N-双（1-甲基乙基）亚磷酰胺], N4-乙酰基-5′-O-（4,4′-二甲氧基三苯甲基）-2′-脱氧胞苷-3′-O-[O-（2-氰基乙基）-N,N′-二异丙基亚]

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About This Item

经验公式（希尔记法）:
C41H50N5O8P
CAS号:
154110-40-4
分子量:
771.84
MDL编号:
MFCD09842112
UNSPSC代码:
12352200
PubChem化学物质编号:
329774867
NACRES:
NA.51

生物来源

non-animal source (no BSE/TSE risk)

质量水平

200

检测方案

≥98% (31P-NMR)
≥99.0% (reversed phase HPLC)

形式

powder

包装

pkg of 12 × 1 g C113080-12x1G
pkg of 12 × 2 g C113080-12x2G

颜色

white to off-white

λ

conforms (UV/VIS Identity)

相容性

configured for PerkinElmer
configured for Polygen

核苷分析

base: deoxycytidine
base protecting group: acetyl
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard

储存温度

-10 to -25°C

SMILES字符串

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C41H50N5O8P/c1-28(2)46(29(3)4)55(52-25-11-23-42)54-36-26-39(45-24-22-38(43-30(5)47)44-40(45)48)53-37(36)27-51-41(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-22,24,28-29,36-37,39H,11,25-27H2,1-7H3,(H,43,44,47,48)/t36-,37+,39+,55?/m0/s1

InChI key

MECWEBCHRKVTNV-RLWDVSNXSA-N

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一般描述

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. DMT-dC(ac) Phosphoramidite is an acetyl-protected DNA phosphoramidite used in fast deprotection chemistry for the rapid and high-yield synthesis of high-purity oligonucleotides. Key Features of dC(ac):
  • Ultrafast deprotection: 10 minutes at 65°C with AMA reagent
  • Key component in oligonucleotide synthesis
  • Industry-standard for fast deprotection chemistry
  • Operating for AMA deprotection methods without changes
  • Consistent lot-to-lot high purity and performance
  • Manufactured under a certified ISO 9001 quality systemThe product belongs to Expedite™and PolyGen® Synthesizers.

法律信息

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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