biological source
algae (red)
description
Predominantly κ and lesser amounts of λ carrageenan
form
powder
color
white to light brown
useful pH range
7.5-10.5 (1.5% in water)
cation traces
Ca: <3.5%, K: <11%, Na: <2.0%
suitability
suitable for gel preparation
storage temp.
room temp
Quality Level
General description
角叉菜胶是来自红藻细胞壁的粘多糖。 它们是由1，3α-1，4β-半乳聚糖组成的阴离子线性聚合物，每个二糖单元含有一个（κ-），两个（ι-）或三个（λ-）硫酸盐。 在离子溶液中，κ-和ι-角叉菜胶自缔合成螺旋结构，分别形成刚性或柔性凝胶。 λ-角叉菜胶不形成螺旋，并且不凝胶化。 角叉菜胶在商业上用作增稠剂和稳定剂。
Application
角叉菜胶被用来抑制体内和体外的免疫反应，其机制被认为涉及对巨噬细胞的选择性细胞病变作用。 由于ι-、κ-和λ-角叉菜胶具有不同程度的硫酸化，因此可以对它们在保护性、抗病毒性和免疫抑制活性方面的差异进行比较研究。
角叉菜胶被用来抑制体内和体外的免疫反应，其机制被认为涉及对巨噬细胞的选择性细胞病变作用。由于ι-、κ-和λ-角叉菜胶具有不同程度的硫酸化，因此可以对它们在保护性、抗病毒性和免疫抑制活性方面的差异进行比较研究。角叉菜胶可用于开发生物材料，如骨移植替代品；用于药物输送的截留容器，如生物芯和封装载体。角叉菜胶用于开发水凝胶。
Preparation Note
从各种海藻中混合制成刚性凝胶。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
植物油/植物胶产品
此项目有
José A Fernández-Romero et al.
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Topical microbicides that block the sexual transmission of HIV and herpes simplex virus 2 (HSV-2) are desperately needed to reduce the incidence of HIV infections worldwide. Previously we completed phase 3 testing of the carrageenan-based gel Carraguard. Although the trial
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The objective of this study was to histologically and histomorphometrically evaluate the efficacy of the new formulations of eggshell-derived calcium carbonate in rats. The study was conducted on 30 adult male rats. Four standardized and circular intrabony defects were created
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Topical microbicides are a promising solution to address the global threat of HIV and other sexually transmitted infections. To be successful, a microbicide not only needs to be biologically functional but also highly acceptable to users. User acceptability of microbicides
Reuben H Fan et al.
NMR in biomedicine, 21(6), 566-573 (2007-11-29)
Integrated diffusion tensor T(2) measurements were made on normal and edematous rat muscle, and the data were fitted with one- and two-compartment models, respectively. Edematous muscle exhibited a short-lived component (T(2) = 28 +/- 6 ms), with diffusion characteristics similar
J K Tobacman
Environmental health perspectives, 109(10), 983-994 (2001-10-25)
In this article I review the association between exposure to carrageenan and the occurrence of colonic ulcerations and gastrointestinal neoplasms in animal models. Although the International Agency for Research on Cancer in 1982 identified sufficient evidence for the carcinogenicity of
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