C0985
Cytidine 3′,5′-cyclic monophosphate sodium salt
≥98% (HPLC)
别名:
cCMP sodium salt
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关于此项目
经验公式（希尔记法）:
C9H11N3O7PNa
化学文摘社编号:
分子量:
327.16
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
259-397-6
MDL number:
产品名称
Cytidine 3′,5′-cyclic monophosphate sodium salt, ≥98% (HPLC)
InChI key
RZAHVNCNTLFRHJ-IAIGYFSYSA-M
InChI
1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1
SMILES string
[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O
description
1 vial contains 50μmol or approximately 16mg
assay
≥98% (HPLC)
form
powder
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Produced by the hydrolysis of cytidine 5′-triphosphate by the enzyme cytidylyl cyclase.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Ping Tai et al.
Molecular endocrinology (Baltimore, Md.), 25(5), 885-893 (2011-02-19)
Activation of the LH receptor (LHR) in Leydig cells results in the phosphorylation of ERK1/2 by cAMP-dependent and cAMP-independent pathways. Here we examine the mechanisms by which cAMP stimulates ERK1/2 phosphorylation. We show that the stimulation of steroidogenesis is not
Sameer B Shah et al.
Neurobiology of disease, 36(1), 11-25 (2009-06-06)
Microtubule-based neuronal transport pathways are impaired during the progression of Alzheimer's disease and other neurodegenerative conditions. However, mechanisms leading to defects in transport remain to be determined. We quantified morphological changes in neuronal cells following treatment with fibrils and unaggregated
Xiangang Zong et al.
The Journal of biological chemistry, 287(32), 26506-26512 (2012-06-21)
Activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated in vivo by direct binding of the second messenger cAMP. This process plays a fundamental role in the fine-tuning of HCN channel activity and is critical for the modulation of cardiac
Todd Michael Seib et al.
Glia, 59(10), 1387-1401 (2011-05-19)
The system x(C)- (Sx(C)-) transporter functions to mediate the exchange of extracellular cystine (L-Cys(2)) and intracellular glutamate (L-Glu). Internalized L-Cys(2) serves as a rate-limiting precursor for the biosynthesis of glutathione (GSH), while the externalized L-Glu can contribute to either excitatory
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