C0742
CKI-7 二盐酸盐
≥98% (HPLC), solid, CK1 inhibitor
别名:
N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺 二盐酸盐
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C11H12ClN3O2S · 2HCl
化学文摘社编号:
分子量:
358.67
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
CKI-7 二盐酸盐, ≥98% (HPLC), solid
SMILES string
Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
InChI key
JUAVTXYOCISSSL-UHFFFAOYSA-N
InChI
1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white to light tan
solubility
H2O: >5 mg/mL
storage temp.
−20°C
Quality Level
相关类别
Biochem/physiol Actions
CKI-7是一种CK1抑制剂；也能抑制SGK、S6K1和MSK1。
CKI-7是一种CK1抑制剂；也能抑制SGK、S6K1和MSK1。 CKI-7与CK1一样能有效抑制SGK。IC50 = 6 μM。
Disclaimer
材料是吸湿性的
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hyun Cheol Kim et al.
European radiology, 24(6), 1386-1393 (2014-03-14)
To evaluate multidetector computed tomography (MDCT) for the prediction of perforation site according to each gastrointestinal (GI) tract site and elapsed time. One hundred and sixty-eight patients who underwent MDCT before laparotomy for GI tract perforation were enrolled and allocated
Xueyuan Guo et al.
Chinese medical journal, 127(6), 1033-1038 (2014-03-14)
Neutrophil/lymphocyte ratio (NLR) has been proposed as a novel marker of systemic inflammation and oxidative stress. The objective of this study was to ascertain the relationship between levels of NLR and recurrence of lone atrial fibrillation (AF) after catheter ablation.
Hanna K Gaggin et al.
JACC. Heart failure, 2(1), 65-72 (2014-03-14)
This analysis aimed to perform a head-to-head comparison of 3 of the promising biomarkers of cardiovascular (CV) outcomes in heart failure (HF)-soluble ST2 (sST2), growth differentiation factor (GDF)-15, and highly-sensitive troponin T (hsTnT)-and to evaluate the role of serial measurement
Masaharu Hata et al.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 190(10), 899-904 (2014-03-14)
Wide surgical excision is the standard treatment for angiosarcoma of the scalp, but many patients are inoperable. Therefore, we investigated the outcome of radiation therapy for angiosarcoma of the scalp. Seventeen patients with angiosarcoma of the scalp underwent radiation therapy
Sandra Krohn et al.
Journal of clinical microbiology, 52(5), 1754-1757 (2014-03-14)
Qualitative and quantitative 16S rRNA gene-based real-time PCR and direct sequencing were applied for rapid detection and identification of bacterial DNA (bactDNA) in 356 ascites samples. bactDNA was detected in 35% of samples, with a mean of 3.24 log copies
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持