所有图片(1)
别名:
(-)- 反 -3,3′,4′5,7-五羟基黄烷, (2S,3R)-2-（3,4-二羟基苯基）-3,4-二氢-1 (2H)-苯并吡喃-3,5,7-三醇
经验公式（希尔记法）:
C15H14O6
CAS号:
分子量:
290.27
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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生物来源
green tea
质量水平
检测方案
≥97% (HPLC)
形式
powder
储存温度
2-8°C
SMILES字符串
O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3
InChI
1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
InChI key
PFTAWBLQPZVEMU-HIFRSBDPSA-N
基因信息
human ... BACE1(23621)
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一般描述
儿茶素是绿茶中主要的黄酮类化合物，占比达90%。(−)-儿茶素在肠道吸收中的生物利用度相对低于(+)-儿茶素。
应用
(-)-儿茶素已用于：
- 检测其对于雌激素受体的结合亲和力
- 作为高效液相色谱(HPLC)法定量检测植物提取物中多酚类物质的参考标准品
- 作为伊朗绿茶茶叶中抗氧化剂定量分析的动力学研究的参考标准品
生化/生理作用
儿茶素具有广泛的生物功效。它可诱发抗病毒和抗癌活性。儿茶素还在糖类和脂质代谢中起重要的调节作用。它可预防脂质积聚。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Ji Hyung Jun et al.
Nature plants, 4(12), 1034-1043 (2018-11-28)
Proanthocyanidins (PAs) are primarily composed of the flavan-3-ol subunits (-)-epicatechin and/or (+)-catechin, but the basis for their different starter and extension unit compositions remains unclear. Genetic and biochemical analyses show that, in the model legume Medicago truncatula, two 2-oxoglutarate-dependent dioxygenases
(+)-Catechin is more bioavailable than (-)-catechin: relevance to the bioavailability of catechin from cocoa
Donovan JL, et al.
Free Radical Research, 40(10), 1029-1034 (2006)
Estrogen-like effects of wine extracts on nitric oxide synthesis in human endothelial cells
Simoncini T, et al.
Maturitas, 70(2), 169-175 (2011)
Green tea catechins: Their use in treating and preventing infectious diseases
Reygaert WC
BioMed Research International, 2018 (2018)
Rajapandiyan Krishnamoorthy et al.
Biomolecules, 9(12) (2019-12-11)
Human gut microbes are a profitable tool for the modification of food compounds into biologically active metabolites. The biological properties of catechins have been extensively investigated. However, the bioavailability of catechin in human blood plasma is very low. This study
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