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Merck
CN

C0567

(-)-儿茶素

from green tea, ≥97% (HPLC), powder, oxidative stress inhibitor

别名:

(-)--3,3′,4′5,7-五羟基黄烷, (2S,3R)-2-(3,4-二羟基苯基)-3,4-二氢-1 (2H)-苯并吡喃-3,5,7-三醇

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关于此项目

经验公式(希尔记法):
C15H14O6
化学文摘社编号:
分子量:
290.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
242-611-7
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
Quality level:
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产品名称

(-)-儿茶素, ≥97% (HPLC), from green tea

biological source

green tea

Quality Level

assay

≥97% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1

InChI key

PFTAWBLQPZVEMU-HIFRSBDPSA-N

Gene Information

human ... BACE1(23621)

General description

儿茶素是绿茶中主要的黄酮类化合物,占比达90%。(−)-儿茶素在肠道吸收中的生物利用度相对低于(+)-儿茶素。

Application

(-)-儿茶素已用于:
  • 检测其对于雌激素受体的结合亲和力
  • 作为高效液相色谱(HPLC)法定量检测植物提取物中多酚类物质的参考标准品
  • 作为伊朗绿茶茶叶中抗氧化剂定量分析的动力学研究的参考标准品

Biochem/physiol Actions

儿茶素具有广泛的生物功效。它可诱发抗病毒和抗癌活性。儿茶素还在糖类和脂质代谢中起重要的调节作用。它可预防脂质积聚。


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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分析证书(COA)

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商品

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research


(+)-Catechin is more bioavailable than (-)-catechin: relevance to the bioavailability of catechin from cocoa
Donovan JL, et al.
Free Radical Research, 40(10), 1029-1034 (2006)
Ji Hyung Jun et al.
Nature plants, 4(12), 1034-1043 (2018-11-28)
Proanthocyanidins (PAs) are primarily composed of the flavan-3-ol subunits (-)-epicatechin and/or (+)-catechin, but the basis for their different starter and extension unit compositions remains unclear. Genetic and biochemical analyses show that, in the model legume Medicago truncatula, two 2-oxoglutarate-dependent dioxygenases
Estrogen-like effects of wine extracts on nitric oxide synthesis in human endothelial cells
Simoncini T, et al.
Maturitas, 70(2), 169-175 (2011)



全球贸易项目编号

货号GTIN
C0567-5MG04061833450826