C0412
伴刀豆球蛋白A 来源于洋刀豆 （刀豆）
Type IV-S, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
别名:
刀豆素 A
产品名称
伴刀豆球蛋白A 来源于洋刀豆 （刀豆）, Type IV-S, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
sterility
γ-irradiated
type
Type IV-S
product line
BioReagent
form
lyophilized powder
technique(s)
cell culture | mammalian: suitable
impurities
salt, essentially free
solubility
PBS: 5 mg/mL, slightly hazy
H2O: soluble, slightly hazy
storage temp.
−20°C
Quality Level
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Analysis Note
据报道，凝集活性以μg/ml表示，并且在Ca2+ 和Mn2+ 浓度为1 mg/ml、pH 6.8的磷酸缓冲盐溶液中进行连续稀释测定。该活性是在25°C下孵育1小时的2%人红细胞悬浮液可以凝集的最低浓度。
Application
来自洋刀豆（刀豆）的伴刀豆球蛋白A已用于以下情形：
- 诱导脾胚芽生殖
- 从B6和lpr脾细胞生成ConA blast靶标
- 刺激雌激素和安慰剂治疗小鼠的脾淋巴细胞
Biochem/physiol Actions
刀豆素 A 无血型特异性，但对末端 α-D-甘露糖基和 α-D-葡糖基残基具有亲和力。需要 Ca2+ 和 Mn2+ 离子存在才能显示活性。刀豆素 A 在 pH 6.5 或更低的条件下解离为二聚体。pH 在 5.8 至 7.0 之间时，刀豆素 A 以四聚体形式存在；pH 高于 7.0 时，形成更高的聚合体。根据聚合程度不同，刀豆素 A 可能显示出具有促有丝分裂的活性。琥珀酰化可以生成一种能够在 pH 高于 5.6 时仍保持二聚体形式的活性二聚体。
wgk
WGK 3
signalword
Danger
hcodes
Hazard Classifications
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
动植物源性产品
此项目有
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