Anti-CSTF3 (N-terminal) antibody produced in rabbit

Cleavage stimulatory factor (CstF3), also called CSTF-77, is a component of CstF heterotrimer. It has a proline-rich domain and the gene is mapped to human chromosome 11p13. CstF3 contains 12 half-A-TPR (HAT) repeats followed by a proline-rich segment.

Anti-CSTF3 (N-terminal) specifically recognizes human CSTF3 (also known as Cleavage stimulation factor 77, CSTF-77, CF-1 77 kDa subunit).

Anti-CSTF3 (N-terminal) antibody produced in rabbit has been used in chromatin immunoprecipitation and immunoblotting.

Cleavage stimulatory factor (CstF3) is required for proper 3′-end cleavage and is critical for the assembly of the CstF complex, bridging both CSTF1 and CSTF2. CSTF3 also interacts directly with the RNA polymerase II C-terminal domain (CTD), but with lower efficiency than CSTF1.

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Store at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.