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主要文件

安全信息

B8776

Sigma-Aldrich

肉毒毒素A 来源于肉毒杆菌

lyophilized powder

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352200

表单

lyophilized powder

运输

dry ice

储存温度

−20°C

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生化/生理作用

Inhibits release of catecholamines from adrenal medulla, acetylcholine at neuromuscular junctions.
Neurotoxin that inhibits release of catecholamines from adrenal medulla; blocks release of acetylcholine at neuromuscular junctions.

外形

Lyophilized powder containing 20 mM HEPES and 1.25% lactose when reconstituted with the volume of water or buffer indicated on the Certifcate of Analysis.

制备说明

When toxin is used for in vitro studies, it is preincubated in a buffer containing 5 mM dithiothreitol for 30 minutes in order to reduce and thereby activate the toxin.

重悬

Reconstitute each 100 μg vial with 100 μL of appropriate buffer. Upon reconstitution, the vial will contain 20 mM HEPES and 1.25% lactose. To insure full recovery of toxin from the vial, include 1 mg/mL BSA in the reconstitution buffer.

其他说明

Handle the toxin gently. Do not vortex. Use sufficient volume of buffer to wash down the walls and stopper. Read all handling information found on SDS prior to reconstitution.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 1 Oral

储存分类代码

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E López-Alonso et al.
Neuroscience letters, 196(1-2), 37-40 (1995-08-18)
Giant liposomes were made from a mixture of asolectin phospholipid vesicles and presynaptic plasma membranes isolated from Torpedo cholinergic nerve endings. Acetylcholine filled giant liposomes were able to release neurotransmitter upon stimulation by the Ca2+ ionophore A23187 and Ca2+. Botulinum

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