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Merck
CN

B7188

Sigma-Aldrich

Blonanserin

≥98% (HPLC)

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About This Item

经验公式(希尔记法):
C23H30FN3
分子量:
367.50
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

white to off-white

溶解性

DMSO: ≥10 mg/mL

创始人

Dainippon Sumitomo

储存温度

room temp

SMILES字符串

CCN1CCN(CC1)c2cc(-c3ccc(F)cc3)c4CCCCCCc4n2

InChI

1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3

InChI key

XVGOZDAJGBALKS-UHFFFAOYSA-N

生化/生理作用

Blonanserin is a D2/5-HT2 receptor antagonist; atypical antipsychotic.

特点和优势

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 4

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Quetiapine-induced insulin resistance after switching from blonanserin despite a loss in both bodyweight and waist circumference.
Yutaro Suzuki et al.
Psychiatry and clinical neurosciences, 66(6), 534-535 (2012-10-17)
Koji Kato et al.
Psychiatry and clinical neurosciences, 65(4), 389-391 (2011-05-17)
The purpose of the present study was to provide preliminary data on the usefulness and safety of blonanserin for patients with delirium in the intensive care unit (ICU). The charts of 32 consecutive patients with delirium in the ICU were
Ming Peng et al.
Journal of chromatographic science, 50(8), 727-732 (2012-05-19)
Blonanserin is a novel atypical antipsychotic agent for the treatment of schizophrenia. Ethyl alcohol, isopropyl alcohol and toluene are utilized in the synthesis route of this bulk drug. A new validated gas chromatographic (GC) method for the simultaneous determination of
Three cases of schizophrenia showing improvement after switching to blonanserin.
Naohiro Kurotaki et al.
Psychiatry and clinical neurosciences, 65(4), 396-397 (2011-06-21)
Tomomi Tenjin et al.
Human psychopharmacology, 27(1), 90-100 (2012-01-27)
The purpose of this study was to evaluate the effects of blonanserin, a novel antipsychotic, on cognitive function in first-episode schizophrenia. Twenty-four antipsychotic-naïve patients with first-episode schizophrenia participated in the study. Blonanserin was given in an open-label design for 8 weeks.

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