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Merck
CN
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安全信息

B7059

Sigma-Aldrich

Monoclonal Anti-Breast Cancer Resistance Protein antibody produced in mouse

~250 μg/mL, clone BXP-21, tissue culture supernatant, aqueous solution

别名:

Anti-ABCG2, Anti-BCRP

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About This Item

MDL编号:
MFCD03791618
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

200

偶联物

unconjugated

抗体形式

tissue culture supernatant

抗体产品类型

primary antibodies

克隆

BXP-21, monoclonal

表单

aqueous solution

分子量

antigen ~70 kDa

种属反应性

human

浓度

~250 μg/mL

技术

flow cytometry: suitable
immunocytochemistry: 1:20-1:50 using acetone-fixed cytospin preparations
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable using pretreated human tissue
immunohistochemistry (frozen sections): 1:20 using acetone-fixed frozen sections
western blot: suitable

同位素/亚型

IgG2a

UniProt登记号

Q9UNQ0

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ABCG2(9429)

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特异性

Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.

免疫原

fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

外形

Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number
SLCD9271
SLBX1798
SLBL6466V
SLBK4403V
SLBF7613

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Cathrine Elisabeth Olsen et al.
Biochemical pharmacology, 144, 63-77 (2017-08-09)
Here we report on the induction of resistance to photodynamic therapy (PDT) in the ABCG2-high human breast cancer cell line MA11 after repetitive PDT, using either Pheophorbide A (PhA) or di-sulphonated meso-tetraphenylchlorin (TPCS2a) as photosensitizer. Resistance to PhA-PDT was associated
Hong Qi et al.
Experimental eye research, 86(1), 34-40 (2007-11-06)
Nerve growth factor (NGF), a member of the neurotrophin family, has been identified as an essential growth factor supporting stem cell self-renewal outside the nervous system and was previously shown to stimulate corneal epithelial proliferation both in vivo and in

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