所有图片(2)
About This Item
经验公式（希尔记法）:
C18H29NO3 · HCl
CAS号:
分子量:
343.89
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
质量水平
方案
>98% (HPLC)
表单
solid
储存条件
desiccated
颜色
white
溶解性
H2O: soluble 36 mg/mL
创始人
Alcon
SMILES字符串
Cl[H].CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
InChI
1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChI key
CHDPSNLJFOQTRK-UHFFFAOYSA-N
基因信息
human ... ADRB1(153)
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应用
Betaxolol hydrochloride has been used as a β1 blocking agent:
- for the preparation of crystals of (R,S)-betaxolol (BE-IV).
- to treat mammalian cells prior cell stimulation experiments.
- to study the solid structure of metoprolol.
生化/生理作用
Betaxolol hydrochloride has the ability to block calcium channels. Betaxolol is a selective β1 adrenoreceptor antagonist. It has neuroprotective effects on retinal neurons.
特点和优势
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Alcon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
A novel ion-exchange carrier based upon liposome-encapsulated montmorillonite for ophthalmic delivery of betaxolol hydrochloride
Huang Y, et al.
International journal of nanomedicine, 12, 1731-1731 (2017)
J Cameron Millar et al.
Investigative ophthalmology & visual science, 52(2), 685-694 (2010-09-24)
To characterize a technique that concurrently assesses all aqueous humor hydrodynamic parameters in mouse eyes. Mouse outflow facility (C) was determined by multiple flow-rate infusion and episcleral venous pressure (Pe) measured by manometry. The animals were then euthanatized, eliminating aqueous
Patrizia Rossi et al.
Acta crystallographica. Section C, Structural chemistry, 75(Pt 2), 87-96 (2019-02-06)
Metoprolol {systematic name: (RS)-1-isopropylamino-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol}, C15H25NO3, is a cardioselective β1-adrenergic blocking agent that shares part of its molecular skeleton with a large number of other β-blockers. Results from its solid-state characterization by single-crystal and variable-temperature powder X-ray diffraction and differential scanning
M Q Rahman et al.
The British journal of ophthalmology, 95(7), 966-970 (2011-01-25)
To report the persistence of glaucoma medical therapy in a database of 1006 patients with ocular hypertension (OHT), normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG) attending the Glaucoma Clinic at Glasgow Royal Infirmary, Glasgow, UK. Analyses have been
Ana Franky Carvalho et al.
Neuroscience letters, 500(1), 82-85 (2011-06-23)
The cannabinoid system is known to interact with a variety of neuromodulators in the central nervous system and impacts diverse behaviors. Previous studies have demonstrated that limbic norepinephrine is a critical determinant in the behavioral expression of cannabinoid-induced aversion. The
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