所有图片(1)
About This Item
经验公式（希尔记法）:
C17H11F3O3
分子量:
320.26
MDL编号:
UNSPSC代码:
12161501
PubChem化学物质编号:
NACRES:
NA.47
推荐产品
产品名称
7- 苄氧羰基-4-(三氟甲基)香豆素, ≥99% (HPLC), solid
质量水平
方案
≥99% (HPLC)
表单
solid
储存温度
−20°C
SMILES字符串
FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12
InChI
1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2
InChI key
WVKLERKKJXUPIK-UHFFFAOYSA-N
基因信息
rat ... Maoa(29253) , Maob(25750)
应用
7-Benzyloxy-4-trifluoromethylcoumarin has been used:
- in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
- in O-dealkylation reaction to determine the activity of CYP3A
- to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)
生化/生理作用
Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.
法律信息
Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Elias M Oziolor et al.
Ecotoxicology (London, England), 26(6), 809-819 (2017-06-08)
There is increasing interest in quantifying the exposure and effects of anthropogenic contaminants in fish. Determination of exposures in wild fish is routinely performed, but methods to investigate potential effects are less established. One of the most relevant approaches would
Manami Nishiwaki et al.
Scientific reports, 10(1), 17503-17503 (2020-10-17)
Hepatocytes are an important tool for in vitro toxicology testing. In addition to primary cultures, a limited number of immortalized cell lines have been developed. We here describe a new cell line, designated as HepaMN, which has been established from
Vamshi K Manda et al.
Phytotherapy research : PTR, 31(12), 1935-1945 (2017-10-27)
Kratom (Mitragyna speciosa), a native herb of Southeast Asia, is widely known for its psychoactive properties. Recent increase in the use of kratom as a recreational drug has increased the risk of its interaction with conventional drugs if taken concomitantly.
Viktoriia Burkina et al.
Molecules (Basel, Switzerland), 25(11) (2020-06-14)
Water from wastewater treatment plants contains concentrations of pharmaceutically active compounds as high as micrograms per liter, which can adversely affect fish health and behavior, and contaminate the food chain. Here, we tested the ability of the common carp hepatic
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