B4750
Nα-苯甲酰-DL-精氨酸 β-萘胺 盐酸盐
trypsin substrate
别名:
BANA, Nα-苯甲酰基-DL-精氨酸-2-萘酰胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C23H25N5O2 · HCl
化学文摘社编号:
分子量:
439.94
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
EC Number:
213-015-4
Beilstein/REAXYS Number:
3823291
MDL number:
产品名称
Nα-苯甲酰-DL-精氨酸 β-萘胺 盐酸盐, trypsin substrate
InChI key
BNGRKDJZQIGWQF-UHFFFAOYSA-N
InChI
1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
SMILES string
Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
assay
≥98% (TLC)
form
powder
solubility
DMF: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
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General description
胰蛋白酶的显色底物。
Application
Nα-苯甲酰基-DL-精氨酸β-萘酰胺盐酸盐在BANA试验中作为底物用于评价Stefin的抑制活性。它也已用作测定胰蛋白酶抑制剂Ki值的底物。
Biochem/physiol Actions
Nα-苯甲酰基-DL-精氨酸-β萘酰胺盐酸盐（BANA）有助于测定组织蛋白酶B和木瓜蛋白酶的活性。BANA测试也有助于确定牙周致病菌的牙周部位数量。由口腔细菌在牙菌斑或舌苔中合成的挥发性硫化物（VSC）的存在可以通过其水解N-苯甲酰基-DL-精氨酸-2-萘酰胺的能力进行比色确认。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Arabidopsis thaliana (L.) Heynh. genotypes limited in their ability to mount either octadecanoid-dependent induced resistance (IR(-)) or systemic acquired resistance (SAR(-)) were used to characterize the roles of these pathways in plant-herbivore interactions. Molecular and biochemical markers of IR were
SAR studies of some acetophenone phenylhydrazone based pyrazole derivatives as anticathepsin agents.
Neera Raghav et al.
Bioorganic chemistry, 75, 38-49 (2017-09-16)
Cathepsins have emerged as promising molecular targets in a number of diseases such as Alzeimer's, inflammation and cancer. Elevated cathepsin's levels and decreased cellular inhibitor concentrations have emphasized the search for novel inhibitors of cathepsins. The present work is focused
Thomas E Rams et al.
Journal of periodontology, 88(10), 1042-1050 (2017-05-19)
The validity of using pretreatment Periodontal Screening and Recording (PSR) index sextant scores to estimate periodontal access surgery needs is evaluated in patients with chronic periodontitis before and after completion of non-surgical periodontal therapy. In 110 adults, pretreatment probing data
Relationship of psychological and oral health statuses with self-perceived halitosis in a Jordanian population: a cross-sectional study
Alzoubi F Q, et al.
BMC Oral Health, 15(1), 89-89 (2015)
Association between atherosclerosis and periodontitis
Lopez N J, et al.
Revista medica de Chile, 139(6), 717-724 (2011)
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