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Merck
CN

B3770

Sigma-Aldrich

(+)-生物素酰胺己酰肼

≥90% (TLC), powder

别名:

BACH, N-(+)-生物素-6-氨基己酰肼, (+)-生物素-ε-氨基己酰基酰肼, (+)-生物素-X-酰肼, (+)-生物素氨基己酰基酰肼

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About This Item

经验公式(希尔记法):
C16H29N5O3S
分子量:
371.50
MDL编号:
UNSPSC代码:
12352125
eCl@ss:
34058011
PubChem化学物质编号:
NACRES:
NC.07

质量水平

方案

≥90% (TLC)

表单

powder

溶解性

DMSO: 25 mg/mL

储存温度

2-8°C

SMILES字符串

[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NN)[C@@]1([H])NC(=O)N2

InChI

1S/C16H29N5O3S/c17-21-14(23)8-2-1-5-9-18-13(22)7-4-3-6-12-15-11(10-25-12)19-16(24)20-15/h11-12,15H,1-10,17H2,(H,18,22)(H,21,23)(H2,19,20,24)/t11-,12-,15-/m0/s1

InChI key

IJJWOSAXNHWBPR-HUBLWGQQSA-N

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应用

具有氨基己基间隔物的生物素化试剂,用于醛基(例如高碘酸盐氧化的糖)和羧酸。通常用于通过腙键形成通过碳水化合物与糖蛋白偶联。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of immunology (Baltimore, Md. : 1950), 127(2), 572-575 (1981-08-01)
Biotin hydrazide was attached covalently to the aldehyde groups produced by periodate oxidation of bovine brain gangliosides. These modified gangliosides were incorporated into mature rat thymocytes by incubation of the biotinyl gangliosides in the culture medium containing these cells. Avidin
Adelaide U P Hain et al.
Journal of medicinal chemistry, 57(11), 4521-4531 (2014-05-03)
Atg8 is a ubiquitin-like autophagy protein in eukaryotes that is covalently attached (lipidated) to the elongating autophagosomal membrane. Autophagy is increasingly appreciated as a target in diverse diseases from cancer to eukaryotic parasitic infections. Some of the autophagy machinery is
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Biochemical and biophysical research communications, 520(1), 152-158 (2019-10-05)
We examined whether chondroitin sulfates (CSs) exert inhibitory effects on heparanase (Hpse), the sole endoglycosidase that cleaves heparan sulfate (HS) and heparin, which also stimulates chemokine production. Hpse-mediated degradation of HS was suppressed in the presence of glycosaminoglycans derived from
Kimberly MacKay et al.
Briefings in functional genomics, 19(4), 292-308 (2020-05-01)
The advent of high-resolution chromosome conformation capture assays (such as 5C, Hi-C and Pore-C) has allowed for unprecedented sequence-level investigations into the structure-function relationship of the genome. In order to comprehensively understand this relationship, computational tools are required that utilize
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Journal of neurochemistry, 46(2), 641-648 (1986-02-01)
beta-nerve growth factor (NGF) was modified by biotinylation via carboxyl group substitution (C-bio-NGF) using biotin hydrazide and the coupling reagent 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide, under reaction conditions that yielded an average of 3 biotin additions per NGF subunit. NGF was also biotinylated through

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