推荐产品
生物来源
bovine artery (USDA-inspected cattle)
包装
pkg of 500,000 cells
制造商/商品名称
Cell Applications, Inc
生长模式
Adherent
核型
2n = 60
形态学
smooth muscle
技术
cell culture | mammalian: suitable
相关疾病
cardiovascular diseases
运输
dry ice
储存温度
−196°C
相关类别
一般描述
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.
Bovine large artery smooth muscle cells (BAOSMC) provide an excellent model system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.
BAOSMC have been utilized in a number of research studies, for example, to:
Bovine large artery smooth muscle cells (BAOSMC) provide an excellent model system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.
BAOSMC have been utilized in a number of research studies, for example, to:
- Elucidate RhoA-dependent serum response signaling pathways (Gudi, 2002); the role of FAK in thrombospondin-1 induced migration of vascular smooth muscle cells (Wang, 2008)
- Demonstrate the relationship between the disturbed flow and proliferation of smooth muscle cells, leading to intima hyperplasia (Fan, 2010); and study interactions between lipoproteins and extracellular matrix, as well as mechanisms of lipoprotein aggregation contributing to atherosclerosis (Sakr, 2001)
- Construct an expression cassette to maximize targeted transgene expression (Dronadula, 2010)
- Test new technologies, such as on-chip contact imaging technique (Liu, 2004; Ji, 2005, 2007; Prakash, 2007), handheld fluorometers (Nelson, 2009) and a “nose on a chip” olfactory sensor (Patel, 2011)
- Study the behavior of smooth muscle cells in 3d environment (Du, 2008) and smooth muscle/endothelial co-cultures (Niwa, 2007; Fan, 2008; Mathura, 2013); describe an origami-like method of generating three-dimensional (3D) cell-laden microstructures (Kuribayashi-Shigetomi, 2012); and design materials for tissue engineering and cardiovascular implants (Mathews, 2006, 2008)
Characterization: positive for smooth muscle cell specific alpha-actin expression.
细胞系来源
Artery
应用
aortic wall contraction, role of smc under normal conditions, blood pressure, distribution of oxygenated blood through systemic circulation
组分
Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
制备说明
- 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
传代培养常规
Please refer to the BAOSMC Culture Protocol.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门