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Merck
CN

B3412

Sigma-Aldrich

小檗碱 半硫酸盐

≥95%

别名:

黄连素

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About This Item

线性分子式:
C20H18NO4 · 1/2SO4
CAS号:
分子量:
384.39
颜色索引号:
75160
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥95%

形式

powder

溶解性

methanol: soluble

SMILES字符串

[O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC

InChI

1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2

InChI key

OJVABJMSSDUECT-UHFFFAOYSA-L

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应用

Fluorescent stain for heparin in mast cells

生化/生理作用

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

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Dong-Gu Kim et al.
Molecular medicine reports, 21(1), 258-266 (2019-11-21)
The major role of inner medullary collecting duct (IMCD) cells is to maintain water and sodium homeostasis. In addition to the major role, it also participates in the protection of renal and systemic inflammation. Although IMCD cells could take part

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Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.

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