B3412
小檗碱 半硫酸盐
≥95%
别名:
黄连素
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关于此项目
线性分子式:
C20H18NO4 · 1/2SO4
化学文摘社编号:
分子量:
384.39
UNSPSC Code:
12171500
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Colour Index Number:
75160
Assay:
≥95%
Form:
powder
Solubility:
methanol: soluble
产品名称
小檗碱 半硫酸盐, ≥95%
InChI
1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2
SMILES string
[O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC
InChI key
OJVABJMSSDUECT-UHFFFAOYSA-L
assay
≥95%
form
powder
solubility
methanol: soluble
Quality Level
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Application
Fluorescent stain for heparin in mast cells
Biochem/physiol Actions
An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Dong-Gu Kim et al.
Molecular medicine reports, 21(1), 258-266 (2019-11-21)
The major role of inner medullary collecting duct (IMCD) cells is to maintain water and sodium homeostasis. In addition to the major role, it also participates in the protection of renal and systemic inflammation. Although IMCD cells could take part
商品
Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.
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