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Merck
CN

B3383

联苯胺 二盐酸盐

≥99% (titration)

别名:

4,4′-二氨基联苯 二盐酸盐

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关于此项目

经验公式(希尔记法):
C12H12N2 · 2HCl
化学文摘社编号:
分子量:
257.16
UNSPSC Code:
12352116
NACRES:
NA.25
PubChem Substance ID:
EC Number:
208-519-6
Beilstein/REAXYS Number:
3914846
MDL number:
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InChI key

RUAXWVDEYJEWRY-UHFFFAOYSA-N

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

SMILES string

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

assay

≥99% (titration)

form

powder

Quality Level

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Application

联苯胺(4,4′-二氨基联苯)是一种环境遗传毒素,能够提高暴露人群的癌症患病风险。联苯胺可用作联苯胺分析过程中的参考材料。联苯胺可用于研究其遗传毒性机理。

Biochem/physiol Actions

实验动物乳腺中的肿瘤引发剂。

Disclaimer

可疑致癌剂

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Yan Cao et al.
Stem cells and development, 24(22), 2660-2673 (2015-07-17)
Autophagy is required for hematopoietic stem cell multilineage differentiation, but the underlying mechanism is unknown. Using a conditional mouse model and human leukemia cells, we uncovered a mechanistic link between autophagy and hematopoietic stem cell differentiation. Loss of autophagy in
Juliana Piva de Almeida et al.
Forensic science international, 206(1-3), 58-61 (2010-07-21)
Bloodstains often constitute the major physical evidence in crime investigation. Diluted blood invisible to the naked eye can be detected through presumptive tests however such tests can damage samples and prevent further processing such as DNA analysis. In this study
Jung Woo Lee et al.
Chemical communications (Cambridge, England), 48(3), 422-424 (2011-11-15)
We report a facile route to synthesize size tunable Fe(3)O(4) nanoparticles (NPs)-carbon nitride nanotube (CNNT) hybrids. These hybrids showing the water-soluble property are proven to exhibit ultra high peroxidase mimetic activity compared to those of pure NPs, where a colorless
Xiaoyu Chen et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(37), 11828-11836 (2012-07-26)
Salts that contain radical cations of benzidine (BZ), 3,3',5,5'-tetramethylbenzidine (TMB), 2,2',6,6'-tetraisopropylbenzidine (TPB), and 4,4'-terphenyldiamine (DATP) have been isolated with weakly coordinating anions [Al(OR(F))(4)](-) (OR(F) = OC(CF(3))(3)) or SbF(6)(-). They were prepared by reaction of the respective silver(I) salts with stoichiometric

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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

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