推荐产品
产品名称
Bone Morphogenetic Protein 6 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
生物来源
human
质量水平
重组
expressed in NSO cells
方案
>95% (SDS-PAGE)
表单
lyophilized powder
效能
0.05-0.15 μg/mL ED50
分子量
30–38 kDa
包装
pkg of 20 μg
储存条件
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... BMP6(654)
相关类别
生化/生理作用
Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.
外形
Lyophilized from 200 ul 0.2 μm filtered solution in 40% acetonitrile, 0.1% trifluoroacetic acid containing 50ug bovine serum albumin per 1 ug as a carrier protein.
分析说明
The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Bone morphogenetic proteins and their receptors: potential functions in the brain.
The Journal of Neuroscience, 51, 139-146 (1998)
Gut, 64(6), 973-981 (2014-07-12)
Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease (NAFLD) and its advanced form non-alcoholic steatohepatitis (NASH) is elusive. The aim of this
Hepatology (Baltimore, Md.), 62(2), 429-439 (2015-01-22)
To identify polymorphisms associated with variability of iron overload severity in HFE-associated hemochromatosis, we performed exome sequencing of DNA from 35 male HFE C282Y homozygotes with either markedly increased iron stores (n = 22; cases) or with normal or mildly increased iron
Experimental hematology, 43(5), 404-413 (2015-01-31)
Hepcidin is the central regulator of systemic iron homeostasis; dysregulation of hepcidin expression causes various iron metabolic disorders, including hereditary hemochromatosis and anemia of inflammation. To identify molecules that modulate hepcidin expression, we developed a bioassay system for hepcidin gene
Journal of experimental & clinical cancer research : CR, 30, 47-47 (2011-05-04)
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not
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