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Merck
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主要文件

安全信息

B2805

Sigma-Aldrich

BMP6, human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

别名:

Bone Morphogenetic Protein 6 human, BMP-6

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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32

产品名称

Bone Morphogenetic Protein 6 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

生物来源

human

质量水平

重组

expressed in NSO cells

方案

>95% (SDS-PAGE)

表单

lyophilized powder

效能

0.05-0.15 μg/mL ED50

分子量

30–38 kDa

包装

pkg of 20 μg

储存条件

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

UniProt登记号

储存温度

−20°C

基因信息

human ... BMP6(654)

生化/生理作用

Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.

外形

Lyophilized from 200 ul 0.2 μm filtered solution in 40% acetonitrile, 0.1% trifluoroacetic acid containing 50ug bovine serum albumin per 1 ug as a carrier protein.

分析说明

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

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Bone morphogenetic proteins and their receptors: potential functions in the brain.
Ebendal, T., et al
The Journal of Neuroscience, 51, 139-146 (1998)
Stephanie Arndt et al.
Gut, 64(6), 973-981 (2014-07-12)
Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease (NAFLD) and its advanced form non-alcoholic steatohepatitis (NASH) is elusive. The aim of this
Christine E McLaren et al.
Hepatology (Baltimore, Md.), 62(2), 429-439 (2015-01-22)
To identify polymorphisms associated with variability of iron overload severity in HFE-associated hemochromatosis, we performed exome sequencing of DNA from 35 male HFE C282Y homozygotes with either markedly increased iron stores (n = 22; cases) or with normal or mildly increased iron
Hiroshi Kawabata et al.
Experimental hematology, 43(5), 404-413 (2015-01-31)
Hepcidin is the central regulator of systemic iron homeostasis; dysregulation of hepcidin expression causes various iron metabolic disorders, including hereditary hemochromatosis and anemia of inflammation. To identify molecules that modulate hepcidin expression, we developed a bioassay system for hepcidin gene
Zhu Xishan et al.
Journal of experimental & clinical cancer research : CR, 30, 47-47 (2011-05-04)
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not

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