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Merck
CN

B1901

Sigma-Aldrich

Bradykinin Fragment 2-9

≥97% (HPLC)

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经验公式(希尔记法):
C44H61N11O10
CAS号:
分子量:
904.02
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥97% (HPLC)

形式

powder

UniProt登记号

储存温度

−20°C

SMILES字符串

NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C2CCCN2C(=O)C(CO)NC(=O)C(Cc3ccccc3)NC(=O)CNC(=O)C4CCCN4C(=O)C5CCCN5)C(O)=O

InChI

1S/C44H61N11O10/c45-44(46)48-20-8-16-30(43(64)65)51-38(59)32(24-28-13-5-2-6-14-28)52-40(61)35-18-10-22-55(35)42(63)33(26-56)53-37(58)31(23-27-11-3-1-4-12-27)50-36(57)25-49-39(60)34-17-9-21-54(34)41(62)29-15-7-19-47-29/h1-6,11-14,29-35,47,56H,7-10,15-26H2,(H,49,60)(H,50,57)(H,51,59)(H,52,61)(H,53,58)(H,64,65)(H4,45,46,48)

InChI key

ZZHVXIPXTCBVBE-UHFFFAOYSA-N

基因信息

Amino Acid Sequence

Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

生化/生理作用

The des-arginine-1 bradykinin (BK) peptide (2-9) has no detectable contractile activity, inhibits ACE (angiotensin converting enzyme) and potentiates BK.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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S Mohammed et al.
Journal of mass spectrometry : JMS, 36(12), 1260-1268 (2001-12-26)
A novel tandem quadrupole mass spectrometer is described that enables gaseous collision-induced dissociation (CID) and surface-induced dissociation (SID) experiments. The instrument consists of a commercially available triple quadrupole mass spectrometer connected to an SID region and an additional, orthogonal quadrupole
B W Busser et al.
The Journal of urology, 160(6 Pt 1), 2267-2273 (1998-11-17)
Bradykinin 1 (B1) receptors have been shown to be upregulated at sites of inflammation. The purpose of this study was to determine the effect of lipopolysaccharide (LPS) on B1 receptor modulation in the isolated mouse bladder. The contractile responses of
Cristiano R Jesse et al.
Pharmacology, biochemistry, and behavior, 91(4), 573-580 (2008-10-22)
The objective of this study was to extend our previous findings by investigating in greater detail the mechanisms that might be involved in the antinociceptive action of p-methoxyl-diphenyl diselenide, (MeOPhSe)(2), in mice. The pretreatment with nitric oxide precursor, l-arginine (600
N P Ewing et al.
Journal of mass spectrometry : JMS, 36(8), 875-881 (2001-08-28)
Apparent gas-phase basicities (GB(app)s) for [M + H]+ of bradykinin, des-Arg1-bradykinin and des-Arg9-bradykinin have been assigned by deprotonation reactions of [M + 2H]2+ in a Fourier transform ion cyclotron resonance mass spectrometer. With a GB(app) of 225.8 +/- 4.2 kcal
G S Bedi et al.
Biochimica et biophysica acta, 842(1), 90-99 (1985-09-27)
Four hybridoma cell lines have been established that secrete monoclonal antibodies to nonapeptide bradykinin. Bradykinin coupled to ovalbumin, using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide as coupling agent, was used to immunize BALB/c mice. Spleen cells from the immunized animals were fused to P3-X63-AG8-653 mouse

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