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About This Item
经验公式（希尔记法）:
C16H13BrO2
CAS号:
分子量:
317.18
MDL编号:
UNSPSC代码:
41106300
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
生物来源
synthetic (organic)
质量水平
方案
≥98% (TLC)
表单
powder
效能
636 nM Ki
溶解性
DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
λmax
224 nm
储存温度
−20°C
SMILES字符串
[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23
InChI
1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
InChI key
BYUCSFWXCMTYOI-ZRDIBKRKSA-N
生化/生理作用
来自P388D巨噬细胞（IC 50 = 8μM）的钙取代磷脂酶A2和镁取代磷脂酸磷酸磷酸酶的强效，不可逆抑制剂；酶激活的不可逆糜蛋白酶抑制剂（K i = 636 nM）。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Kasey K Pham et al.
Genome, 60(9), 720-732 (2017-04-27)
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Masahiro Nagahama et al.
Toxins, 10(5) (2018-05-23)
Clostridium perfringens iota-toxin is a binary actin-ADP-ribosylating toxin composed of the enzymatic component Ia and receptor binding component Ib. Ib binds to a cell surface receptor, forms Ib oligomer in lipid rafts, and associates with Ia. The Ia-Ib complex then
Ulrika Christerson et al.
Cells, 8(7) (2019-07-07)
Increased activity of secretory phospholipases A2 (sPLA2) type-II was previously observed in ileum of Crohn's disease (CD). Our aims were to explore the involvement of calcium-independent (i)PLA2β in the release of sPLA2s from the human mast cell (MC) line (HMC-1)
Franz J Ricken et al.
PLoS neglected tropical diseases, 11(5), e0005636-e0005636 (2017-05-26)
Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis. The inflammatory response to this infection is influenced by the interaction of the parasite with the host. We aimed to analyze human liver lesions infected with Echinococcus multilocularis
Anne Katrine Kehler et al.
Current eye research, 37(6), 500-507 (2012-05-15)
Inhibition of VEGF in the eye is an important treatment modality for reducing proliferation and migration of retinal pigment epithelium (RPE) in age-related macular degeneration (AMD). Additionally, previous studies suggest calcium-independent phospholipase A(2) group VIA (iPLA(2)-VIA) to be a potential
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