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经验公式(希尔记法):
C16H13BrO2
化学文摘社编号:
分子量:
317.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
MDL number:
InChI
1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
SMILES string
[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23
InChI key
BYUCSFWXCMTYOI-ZRDIBKRKSA-N
biological source
synthetic (organic)
assay
≥98% (TLC)
form
powder
potency
636 nM Ki
solubility
DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.), degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
λmax
224 nm
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
来自P388D巨噬细胞(IC 50 = 8μM)的钙取代磷脂酶A2和镁取代磷脂酸磷酸磷酸酶的强效,不可逆抑制剂;酶激活的不可逆糜蛋白酶抑制剂(K i = 636 nM)。
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
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