一般描述
脑提取物具有高含量的脂质,尤其是多不饱和脂肪酸(PUFA)。黑质和纹状体的提取物中铁含量很高。
应用
牛脑的脑提取物已被用于:
- 在脂质结合试验中用于制备小的单层囊泡
- 在脂质体和蛋白质自聚集测定中,有助于磷酸肌醇的回收,并终止磷脂酰肌醇5-磷酸(PtdIns5P)和PtdIns4P检测的反应
生化/生理作用
脑脂质可参与细胞信号转导、膜组织、运输蛋白修饰、相互作用和能量存储。
包装
密封安瓿瓶。
其他说明
包含磷脂酰肌醇、磷脂酰丝氨酸和其他脑脂质。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Low C, et al.
Biophysical Journal, 95(9), 4315-4323 (2008)
Cholesterol and Fat Metabolism in Alzheimer?s Disease
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders, 161-193 (2017)
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D
Freye-MC, et al.
Biochemistry, 42(3), 620-630 (2003)
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)
Qing Lu et al.
Molecular biology of the cell, 22(22), 4268-4278 (2011-10-04)
Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms.
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