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Merck
CN

B1125

浴铜灵二磺酸 二钠盐

7.2-9.1% purity dry basis (ICP), powder

别名:

2,9-二甲基-4,7-二苯基-1,10-邻二氮杂菲二磺酸 二钠盐, 浴铜灵二磺酸二钠盐

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关于此项目

经验公式(希尔记法):
C26H18N2Na2O6S2
化学文摘社编号:
分子量:
564.54
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47
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产品名称

浴铜灵二磺酸 二钠盐, for spectrophotometric det. of Cu, Fe

SMILES string

[Na+].[Na+].[S](=O)(=O)([O-])c1c(nc2c3nc(c(c(c3ccc2c1c5ccccc5)c4ccccc4)[S](=O)(=O)[O-])C)C

InChI

1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2

InChI key

RNGKZLRAVYPLJC-UHFFFAOYSA-L

assay

7.2-9.1% dry basis (ICP)

form

powder

quality

for spectrophotometric det. of Cu, Fe

technique(s)

titration: 90% using HCLO4 (Dry Basis)

color

white to beige

solubility

H2O: 50 mg/mL

suitability

suitable for determination of copper

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

  • 浴铜灵二磺酸二钠盐已被用作铜螯合剂,用于拟南芥幼苗的特异性测定。
  • 它已被用作电子链相关自由基生成的抑制剂,用于测定细胞中的超氧化物歧化酶。
  • 它已被作为铜螯合剂添加至锥虫培养基中,用于稳定半胱氨酸。

General description

浴铜灵二磺酸是一种强效铜螯合剂。它可用于测定生物样品中的铜和铁。

Other Notes

异构体混合物

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jennifer Lowe et al.
The Journal of biological chemistry, 279(25), 25986-25994 (2004-04-14)
Ccc2p is homologous to the human Menkes and Wilson copper ATPases and is herein studied as a model for human copper transport. Most studies to date have sought to understand how mutations in the human Menkes or Wilson genes impair
Minglin Lang et al.
Neurobiology of aging, 34(11), 2604-2612 (2013-07-06)
Disruption of copper homeostasis has been implicated in Alzheimer's disease (AD) during the last 2 decades; however, whether copper is a friend or a foe is controversial. Within a genetically tractable Drosophila AD model, we manipulated the expression of human
Shinya Ogawa et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 34-36 (2012-11-17)
HPLC eluent systems employing acetonitrile and methanol were evaluated for the quantitation of glutathione (GSH) and phytochelatin (PC(n)), a family of peptides implicated in heavy-metal detoxification in higher plants. The detection system is based on the dequenching of copper(I)-bathocuproine disulfonate
Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue.
Weydert CJ and Cullen JJ
Nature Protocols, 5, 51-66 (2010)
Shinya Ogawa et al.
Analytical chemistry, 81(21), 9199-9200 (2009-09-30)
Reoptimization of analytical conditions was performed for a high-performance liquid chromatographic (HPLC) detection system for Cu(I) chelators based on the dequenching of Cu(I)-bathocuproine disulfonate complexes that occurs in the presence of Cu(I) chelators. The revision corrects for emission and excitation

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