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Merck
CN

B0390

Sigma-Aldrich

胆红素氧化酶 来源于疣孢漆斑菌

greener alternative

lyophilized powder, 15-65 units/mg protein

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别名:
MvBOx, 胆红素:氧氧化还原酶
CAS号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54

生物来源

fungus (Myrothecium verrucaria)

质量水平

形式

lyophilized powder

比活

15-65 units/mg protein

组成

Protein, ≥15% biuret

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

环保替代产品特性

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

技术

toxicology assay: suitable

环保替代产品分类

运输

dry ice

储存温度

−20°C

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一般描述

我们致力于为您带来更加绿色的替代产品,这些产品遵守一项或多项绿色化学12项原则。对于生物燃料电池研究,本品已根据提高能效和防止废物原则进行了改进。详情参阅《biofiles》文章

胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员,常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成,含有4个铜离子组成的2个活性位点。研究领域:细胞凋亡

应用

胆红素氧化酶用于降解胆红素。胆红素氧化酶可用于测定黄疸标本中的游离血红蛋白 。在染料流出液脱色方面也有潜在的应用,是治疗新生儿黄疸的潜在药物
胆红素氧化酶(来自疣孢漆斑菌)已用于消除胆红素干扰。它还可用于通过荧光素衍生物(FS)标记和多元校正进行直接胆红素(dBR)和总胆红素(tBR)分析。

生化/生理作用

胆红素氧化酶 (BOD) 是一种催化胆红素氧化为胆绿素的多铜氧化酶。氧是电子受体,被还原成水。在血清的医学检查中,该酶用于血清中胆红素的诊断分析。它也被用作中性条件下工作的生物燃料电池阴极的酶催化剂。是一种单体蛋白,分子量为 60 kDa,在中性 pH 下具有高反应性。BOD 参与卟啉和叶绿素代谢。
胆红素氧化酶(BOD)可氧化漆酶底物。

单位定义

在 37°C、pH 8.4 时,1 个单位每分钟将氧化 1.0 μmol 的胆红素。

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

分析证书(COA)

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Luciano Dos Santos et al.
Physical chemistry chemical physics : PCCP, 12(42), 13962-13974 (2010-09-21)
The 'blue copper' enzyme bilirubin oxidase from Myrothecium verrucaria shows significantly enhanced adsorption on a pyrolytic graphite 'edge' (PGE) electrode that has been covalently modified with naphthyl-2-carboxylate functionalities by diazonium coupling. Modified electrodes coated with bilirubin oxidase show electrocatalytic voltammograms
A'edah Abu-Bakar et al.
Toxicology and applied pharmacology, 257(1), 14-22 (2011-08-30)
We have previously shown that bilirubin (BR), a breakdown product of haem, is a strong inhibitor and a high affinity substrate of the mouse cytochrome P450 2A5 (CYP2A5). The antioxidant BR, which is cytotoxic at high concentrations, is potentially useful
Kimihiko Mizutani et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 66(Pt 7), 765-770 (2010-07-08)
Bilirubin oxidase (BOD), a multicopper oxidase found in Myrothecium verrucaria, catalyzes the oxidation of bilirubin to biliverdin. Oxygen is the electron acceptor and is reduced to water. BOD is used for diagnostic analysis of bilirubin in serum and has attracted
Laith Hussein et al.
Physical chemistry chemical physics : PCCP, 13(13), 5831-5839 (2011-02-18)
The fabrication process of buckypapers (BPs) made from stable suspensions of as-received or functionalized multi-walled carbon nanotubes (MWCNTs) with high purity (97.5 wt%, Baytubes), their characterization and their utilization towards novel biofuel cell electrode applications are reported. The BPs can
Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method.
Jabs CM, et al.
Clinical Chemistry, 36(1), 81-87 (1990)

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