B019
盐酸酚苄明 盐酸盐
≥97%, powder
别名:
N-(2-氯乙基)-N-(1-甲基-2-苯氧乙基)苄胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C18H22ClNO · HCl
化学文摘社编号:
分子量:
340.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-569-7
MDL number:
InChI key
VBCPVIWPDJVHAN-UHFFFAOYSA-N
InChI
1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H
SMILES string
Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2
assay
≥97%
form
powder
color
white
solubility
H2O: slightly soluble, alcohol: soluble, propylene glycol: soluble
originator
Wellspring
storage temp.
2-8°C
Quality Level
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
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Biochem/physiol Actions
钙调蛋白拮抗剂；α-肾上腺素受体拮抗剂。
Features and Benefits
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
João Walter S Silveira et al.
Molecular pain, 6, 17-17 (2010-03-25)
Descending pronociceptive pathways may be implicated in states of persistent pain. Paw skin incision is a well-established postoperative pain model that causes behavioral nociceptive responses and enhanced excitability of spinal dorsal horn neurons. The number of spinal c-Fos positive neurons
Brian T Welch et al.
Radiology, 258(1), 301-307 (2010-10-26)
To assess safety, technical success, complications, and hemodynamic changes associated with the adrenal cryoablation procedure. This retrospective review was approved by the institutional review board, with waiver of informed consent, and was compliant with the Health Insurance Portability and Accountability
Yu Zhu et al.
Endocrine, 38(2), 254-259 (2010-11-04)
The objective of this article is to evaluate the efficacy of Doxazosin Mesylate Controlled Release Tablets for preoperative treatment of patients with pheochromocytoma. Between 2003 and 2008, 67 patients with confirmed diagnoses of pheochromocytoma were enrolled in this study. According
H Bruynzeel et al.
The Journal of clinical endocrinology and metabolism, 95(2), 678-685 (2009-12-08)
Surgery on pheochromocytoma carries a risk for hemodynamic (HD) instability. The aim of this study was to identify preoperative risk factors for intraoperative HD instability. In addition, efficacy of pretreatment with the alpha-adrenergic receptor (alpha) antagonists phenoxybenzamine (PXB) and doxazosin
P A van Zwieten et al.
Annals of the New York Academy of Sciences, 522, 351-360 (1988-01-01)
A survey is given of the interaction between alpha-adrenoceptor-triggered vasoconstriction and the influx of extracellular calcium ions. This problem was investigated by studying the influence of calcium entry blockers (CEB) on the vasoconstriction induced by several types of alpha 2-
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