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If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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B016

Sigma-Aldrich

Benoxathian hydrochloride

solid

别名:

2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride

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About This Item

经验公式（希尔记法）:
C19H23NO4S · HCl
CAS号:
92642-97-2
分子量:
397.92
MDL编号:
MFCD00055188
UNSPSC代码:
12352202
PubChem化学物质编号:
24277758
NACRES:
NA.77
价格与库存信息目前不能提供

表单

solid

颜色

white

溶解性

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.)
ethanol: soluble
isopropanol: soluble

SMILES字符串

Cl.COc1cccc(OC)c1OCCNCC2CSc3ccccc3O2

InChI

1S/C19H23NO4S.ClH/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14;/h3-9,14,20H,10-13H2,1-2H3;1H

InChI key

OWRADFDDJVNMGL-UHFFFAOYSA-N

基因信息

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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2263222630PHL80965
奎尼丁 盐酸盐 一水合物 technical grade

Q0750

奎尼丁 盐酸盐 一水合物

奎宁 盐酸盐 二水合物 tested according to Ph. Eur.

22632

奎宁 盐酸盐 二水合物

奎宁 盐酸盐 二水合物 BioReagent, suitable for fluorescence, ≥98.0% (NT)

22630

奎宁 盐酸盐 二水合物

(-)-二氢奎宁 phyproof® Reference Substance

PHL80965

(-)-二氢奎宁

grade

technical grade

grade

-

grade

-

grade

primary reference standard

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

impurities

-

impurities

≤10% dihydroquinine hydrochloride (HPLC)

impurities

-

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

-

Gene Information

-

Gene Information

-

生化/生理作用

Selective α1-adrenoceptor antagonist.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
117H46572
117H4657

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M B Hussain et al.
British journal of pharmacology, 122(5), 849-858 (1998-02-12)
1. The subtype of alpha1-adrenoceptor mediating contractions to phenylephrine of the rat thoracic aorta, mesenteric artery and pulmonary artery were investigated by use of antagonists which show selectivity between the cloned alpha1-adrenoceptor subtypes in binding studies. 2. Cumulative concentration-contraction curves
C H Brown et al.
The Journal of physiology, 507 ( Pt 3), 831-842 (1998-05-23)
1. We have tested the hypothesis that morphine withdrawal excitation of oxytocin neurones that follows from administration of naloxone to morphine-dependent rats is a consequence of excitation of noradrenergic neurones. 2. Female rats were made morphine dependent by intracerebroventricular (i.c.v.)
S Ma et al.
Journal of neuroendocrinology, 17(11), 761-769 (2005-10-13)
Chronic intermittent cold stress sensitises activation of the hypothalamic-pituitary-adrenal (HPA) axis by novel acute stress. We have shown that enhanced noradrenergic function in limbic forebrain contributes to HPA sensitisation. In the present study, we investigated whether chronic intermittent cold also
Jessica A Cardin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(35), 7745-7753 (2004-09-03)
Norepinephrine (NE) plays a complex role in the behavioral state-dependent regulation of sensory processing. However, the role of forebrain NE action in modulating high-order sensory activity has not been directly addressed. In this study, we take advantage of the discrete
Derek Lupinsky et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(22), 7624-7633 (2010-06-04)
While stressors are known to increase medial prefrontal cortex (PFC) glutamate (GLU) levels, the mechanism(s) subserving this response remain to be elucidated. We used microdialysis and local drug applications to investigate, in male Long-Evans rats, whether the PFC GLU stress
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