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Merck
CN

B016

Sigma-Aldrich

Benoxathian hydrochloride

solid

别名:

2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride

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About This Item

经验公式(希尔记法):
C19H23NO4S · HCl
CAS号:
分子量:
397.92
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

表单

solid

质量水平

颜色

white

溶解性

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.)
ethanol: soluble
isopropanol: soluble

SMILES字符串

Cl.COc1cccc(OC)c1OCCNCC2CSc3ccccc3O2

InChI

1S/C19H23NO4S.ClH/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14;/h3-9,14,20H,10-13H2,1-2H3;1H

InChI key

OWRADFDDJVNMGL-UHFFFAOYSA-N

基因信息

生化/生理作用

Selective α1-adrenoceptor antagonist.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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A J Douglas et al.
Journal of neuroendocrinology, 17(1), 40-48 (2005-02-22)
We investigated whether changes in noradrenaline neurotransmission in the hypothalamus could explain the hyporesponsiveness of the hypothalamic-pituitary-adrenal (HPA) axis in late pregnancy. Noradrenaline release within the hypothalamic paraventricular nucleus in response to swim stress, as estimated by microdialysis and high-performance
Y Madrero et al.
British journal of pharmacology, 119(8), 1563-1568 (1996-12-01)
1. The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-O-methylboldine) and glaucine (2,9-O-dimethylboldine) and alpha 1-adrenoceptor subtypes was studied by examining [3H]-prazosin competition binding in rat cerebral cortex. WB 4101 and benoxathian were used as selective
G J Marek et al.
European journal of pharmacology, 305(1-3), 95-100 (1996-06-03)
Pharmacological techniques have defined the existence of two different alpha 1-adrenoceptors, the alpha 1A- and alpha 1B-adrenoceptor subtypes and both of these receptors have been cloned in addition to a cloned alpha 1d-adrenoceptor. A subpopulation of interneurons in layer III
Adrenoceptors in normal and malignant human melanocytes.
A C Scarparo et al.
Archives of dermatological research, 292(5), 265-267 (2000-06-27)
A Douglas et al.
Endocrinology, 142(2), 633-644 (2001-02-13)
Oxytocin secretion is important for the normal progress of parturition in the rat. We tested the hypotheses that contractions of the uterus before pup delivery activate oxytocin neurons, and that they do so via a noradrenergic projection. In anesthetized 22-day

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