推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
分子量
61 kDa
种属反应性
mouse, guinea pig, horse, human, canine, rat, rabbit
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
储存温度
−20°C
基因信息
human ... CYP1B1(1545)
免疫原
The immunogen for anti-CYP1B1 antibody: synthetic peptide derected towards the middle region of human CYP1B1
应用
Anti-CYP1B1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
Cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1) is a member of cytochrome P450 superfamily of monooxygenases. CYP1B1 is localized to the endoplasmic reticulum. It metabolizes polycyclic aromatic hydrocarbon and 17β-estradiol and is possibly involved in the metabolism of signaling molecule involved in the development of the eye. Mutations in CYP1B1 are associated with primary congenital glaucoma and congenital anterior staphylomas.
序列
Synthetic peptide located within the following region: AVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVMPWLQY
外形
Lyophilized from PBS buffer with 2% sucrose
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
L P Madhubhani P Hemachandra et al.
Cancer prevention research (Philadelphia, Pa.), 7(5), 505-515 (2014-03-07)
The risk of developing hormone-dependent cancers with long-term exposure to estrogens is attributed both to proliferative, hormonal actions at the estrogen receptor (ER) and to chemical carcinogenesis elicited by genotoxic, oxidative estrogen metabolites. Nontumorigenic MCF-10A human breast epithelial cells are
The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.
M R Haussler et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 13(3), 325-349 (1998-04-03)
Douglas B Gould et al.
The International journal of developmental biology, 48(8-9), 1015-1029 (2004-11-24)
Development of the ocular anterior segment involves a series of inductive interactions between neural ectoderm, surface ectoderm and periocular mesenchyme. The timing of these events is well established but less is known about the molecular mechanisms involved. Various genes that
Ramzi Al Judaibi et al.
Clinical ophthalmology (Auckland, N.Z.), 8, 445-448 (2014-03-05)
Here, we present two patients with congenital anterior staphyloma, with mutations in the CYP1B1 gene. We reviewed the medical records, including the genetic analysis. Two unrelated patients presented with congenital anterior staphylomas. Both patients showed mutations in the CYP1B1 gene.
Milana Kokosar et al.
Scientific reports, 6, 22883-22883 (2016-03-16)
Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation in adipose tissue from 64 women with PCOS and 30
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