推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
34 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... SLAMF6(114836)
免疫原
Synthetic peptide directed towards the N terminal region of human SLAMF6
应用
Anti-SLAMF6 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
生化/生理作用
SLAM family member 6 (SLAMF6) is a type I transmembrane protein that is involved in natural killer (NK) cell activation in association with SH2 domain-containing phosphatases (SHPs). It is expressed on NK, T and B cells.
序列
Synthetic peptide located within the following region: EIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTSAKLSSYT
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Timothy J Wilson et al.
PloS one, 9(3), e92184-e92184 (2014-03-20)
SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of
Laurence Menard et al.
The Journal of allergy and clinical immunology, 133(4), 1149-1161 (2014-01-01)
Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) can mediate the function of SLAM molecules, which have been proposed to be involved in the development of autoimmunity in mice. We sought to determine whether the SLAM/SAP pathway regulates the establishment of
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