生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
74 kDa
种属反应性
guinea pig, human
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PIGO(84720)
一般描述
The previously assigned protein identifier B1AML3 has been merged into Q8TEQ8. Full details can be found on the UniProt database.
免疫原
Synthetic peptide directed towards the N terminal region of human PIGO
应用
Anti-PIGO antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
生化/生理作用
Phosphatidylinositol glycan anchor biosynthesis, class O (PIGO; HPMRS2) protein is involved in the biosynthesis of glycosylphosphatidylinositol anchor that is present on blood cells and anchors the cell surface proteins. Mutations in PIGO gene results in hyperphosphatasia with mental retardation (HPMRS).
序列
Synthetic peptide located within the following region: LIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRS
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
T Kinoshita et al.
Current opinion in chemical biology, 4(6), 632-638 (2000-12-05)
The pathway for glycosylphosphatidylinositol-anchor biosynthesis consists of at least 10 reaction steps. Many of the genes encoding the enzymes and regulators involved in this pathway have been recently cloned and their products characterised. These studies have revealed the common and
Peter M Krawitz et al.
American journal of human genetics, 91(1), 146-151 (2012-06-12)
Hyperphosphatasia with mental retardation syndrome (HPMRS), an autosomal-recessive form of intellectual disability characterized by facial dysmorphism, seizures, brachytelephalangy, and persistent elevated serum alkaline phosphatase (hyperphosphatasia), was recently shown to be caused by mutations in PIGV, a member of the glycosylphosphatidylinositol
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