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Merck
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安全信息

AV48166

Sigma-Aldrich

Anti-EEF1A1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

别名:

Anti-CCS-3, Anti-CCS3, Anti-EEF-1, Anti-EEF1A, Anti-EF-Tu, Anti-EF1A, Anti-Eukaryotic translation elongation factor 1 α 1, Anti-FLJ25721

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

lyophilized powder

分子量

50 kDa

种属反应性

pig, rat, mouse, rabbit, horse, human, canine

技术

western blot: suitable

免疫原序列

SGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKA

NCBI登记号

UniProt登记号

储存温度

−20°C

基因信息

human ... EEF1A1(1915)

一般描述

Eukaryotic translation elongation factor 1 α 1 (EEF1A1) regulates the transport of aminoacyl tRNA to the ribosome. Downreguation of eEF1A1 is known to induce cell death in tetraploids. Studies have reported that EEF1A1 functions as a target for the male contraceptive, gamendazole, in rat sertoli cells.
Rabbit Anti-EEF1A1 antibody recognizes chicken, canine, pig, human, mouse, and rat EEF1A1.

免疫原

synthetic peptide corresponding to a region of human EEF1A1 with an internal ID of P28675

应用

Rabbit Anti-EEF1A1 antibody is suitable for western blot applications at a concentration of 2.5μg/ml.

外形

Lyophilized from PBS buffer with 2% sucrose

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Joseph S Tash et al.
Biology of reproduction, 78(6), 1139-1152 (2008-01-26)
Gamendazole was recently identified as an orally active antispermatogenic compound with antifertility effects. The cellular mechanism(s) through which these effects occur and the molecular target(s) of gamendazole action are currently unknown. Gamendazole was recently designed as a potent orally active
Y Kobayashi et al.
Cell death and differentiation, 16(1), 139-150 (2008-09-30)
When duplicated sister chromatids are not properly compacted in mitosis, chromosomes are mis-segregated, inducing genetically unstable tetraploidy known to facilitate aneuploid malignancies. Here, we show that tetraploid cells produced by impaired chromosomal condensation are eliminated by a novel type of

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