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安全信息

AV48140

Sigma-Aldrich

Anti-PGK1 (AB1) antibody produced in rabbit

affinity isolated antibody

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别名:
Anti-MGC117307, Anti-MGC142128, Anti-MGC8947, Anti-MIG10, Anti-PGKA, Anti-Phosphoglycerate kinase 1
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

44 kDa

种属反应性

horse, sheep, bovine, rat, human, guinea pig, dog, mouse, rabbit

浓度

0.5 mg - 1 mg/mL

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... PGK1(5230)

一般描述

Phosphoglycerate kinase 1 (PGK1) is an enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate during glycolysis. PGK1 expression has been correlated to CXCR4 expression, survival and bone marrow metastasis in neuroblastoma patients.
Rabbit Anti-PGK1 antibody recognizes bovine, human, mouse, rat, and canine PGK1.

免疫原

Synthetic peptide directed towards the N terminal region of human PGK1

应用

Rabbit Anti-PGK1 antibody has been used as a loading control in immunoblotting assays. The product is suitable at a concentration of 0.5μg/ml for western blots.

生化/生理作用

PGK1 is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The protein may also act as a cofactor for polymerase alpha.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

序列

Synthetic peptide located within the following region: PEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Helen M Ameis et al.
PloS one, 8(12), e83701-e83701 (2014-01-01)
A close relationship between phosphoglycerate kinase 1 (PGK1) and the CXCR4/SDF1 axis (chemokine receptor 4/stromal cell derived factor 1) has been shown for several cancers. However, the role of PGK1 has not been investigated for neuroblastoma, and PGK1 might be

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