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安全信息

AV48138

Sigma-Aldrich

Anti-PGAM2 antibody produced in rabbit

affinity isolated antibody

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别名:
Anti-MGC88743, Anti-PGAMM, Anti-Phosphoglycerate mutase 2 (muscle)
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

29 kDa

种属反应性

human

浓度

0.5 mg - 1 mg/mL

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... PGAM2(5224)

一般描述

Phosphoglycerate mutase 2 (muscle) (PGAM2) catalyzes the the conversion of 3-phosphoglycrate to 2-phosphoglycerate during glucolysis. Genetic alterations in PGAM2 have been linked to muscle phosphoglycerate mutase deficiency and Greig cephalopolysyndactyly syndrome.
Rabbit Anti-PGAM2 antibody recognizes human, mouse, rat, zebrafish, and pig PGAM2.

免疫原

Synthetic peptide directed towards the N terminal region of human PGAM2

应用

Rabbit Anti-PGAM2 antibody is suitable for western blot applications at a concentration of 1μg/ml.

生化/生理作用

PGAM2 is the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. It can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.

序列

Synthetic peptide located within the following region: MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKM

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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K Wagner et al.
Genomics, 8(3), 487-491 (1990-11-01)
Greig cephalopolysyndactyly syndrome (GCPS) is an autosomal dominant disorder that has been mapped to 7p13. We have investigated two patients with GCPS and a cytogenetically visible microdeletion of the short arm of chromosome 7 with gene probes that have been

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