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安全信息

AV46637

Sigma-Aldrich

Anti-UST antibody produced in rabbit

IgG fraction of antiserum

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别名:
Anti-2OST, Anti-Uronyl-2-sulfotransferase
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

48 kDa

种属反应性

guinea pig, rabbit, horse, rat, human, dog, mouse

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... UST(10090)

免疫原

Synthetic peptide directed towards the C terminal region of human UST

应用

Anti-UST antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/mL. It is also useful for immunohistochemistry at a concentration of 4-8μ/mL.

生化/生理作用

UST (Uronyl-2-sulfotransferase) gene encodes for an enzyme that transfers sulfate to the 2-position of uronyl residues, in iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate. In chondroitin sulfate the sulfate group transfer occurs from 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to position 2 of the GlcA residue.

序列

Synthetic peptide located within the following region: YFKGVLSIYKDPEHRKLGNMTVTVKKTVPSPEAVQILYQRMRYEYEFYHY

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Shiori Ohtake et al.
The Journal of biological chemistry, 280(47), 39115-39123 (2005-09-30)
We have shown previously that a highly sulfated sequence, GalNAc(4,6-SO(4))-GlcA(2SO(4))-GalNAc(6SO(4)), is present at the nonreducing terminal of chondroitin sulfate (CS), and this structure was synthesized from a unique sequence, GalNAc(4SO(4))-GlcA(2SO(4))-GalNAc(6SO(4)), by sulfation with N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase. Uronosyl 2-O-sulfotrasferase (2OST), which
M Kobayashi et al.
The Journal of biological chemistry, 274(15), 10474-10480 (1999-04-03)
A partial-length human cDNA with a predicted amino acid sequence homologous to a previously described heparan sulfate iduronyl 2-sulfotransferase (Kobayashi, M., Habuchi, H., Yoneda, M., Habuchi, O., and Kimata, K. (1997) J. Biol. Chem. 272, 13980-13985) was obtained by searching

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