推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
分子量
16 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
储存温度
−20°C
基因信息
human ... SOD1(6647)
一般描述
Superoxide dismutase 1, soluble (aMyotrophic lateral sclerosis 1 (adult)) (SOD1, ALS1, ALS, IPOA, SOD) is a copper-zinc enzyme that destroys free superoxide radicals in the cytoplasm and mitochondrial inter-membrane space of cells. Mutated SOD1 is linked to familial amyotrophic lateral sclerosis (ALS).
特异性
Anti-SOD1 polyclonal antibody reacts with human superoxide dismutase 1.
免疫原
The immunogen for anti-SOD1 antibody: synthetic peptide derected towards the N terminal of human SOD1
应用
Anti-SOD1 polyclonal antibody is used to tag superoxide dismutase 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of superoxide dismutase 1 in cellular oxidative stress defense and as a causative agent in familial amyotrophic lateral sclerosis (ALS).
序列
Synthetic peptide located within the following region: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHE
外形
Lyophilized from PBS buffer with 2% sucrose
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
K Marosi et al.
Neuroscience, 226, 21-28 (2012-09-18)
Exercise can exert beneficial effects on cognitive functions of older subjects and it can also play an important role in the prevention of neurodegenerative diseases. At the same time it is perceivable that limited information is available on the nature
Lijun Wang et al.
Neurobiology of disease, 71, 317-324 (2014-08-20)
Approximately 20% of familial amyotrophic lateral sclerosis (FALS) cases are caused by mutant superoxide dismutase type 1 (mtSOD1). Although the mechanisms of mtSOD1-induced toxicity remain poorly understood, evidence suggests that accumulation of misfolded SOD1 is fundamental to its toxicity and
Michelle L Thompson et al.
Disease models & mechanisms, 7(2), 233-243 (2013-12-07)
Molecular mechanisms underlying neurodegenerative diseases converge at the interface of pathways impacting cellular stress, protein homeostasis and aging. Targeting the intrinsic capacities of neuroprotective proteins to restore neuronal function and/or attenuate degeneration represents a potential means toward therapeutic intervention. The
Maryam Amirazodi et al.
BioMed research international, 2022, 8638714-8638714 (2022-12-21)
Mitochondrial dysfunction and increased oxidative stress cause damage to cells which can lead to the aging process and age-related diseases. Antioxidants such as resveratrol and high-intensity exercise can benefit oxidative damage prevention. This study is aimed at evaluating the effects
Kouji Komatsu et al.
Reproduction (Cambridge, England), 147(5), 627-638 (2014-01-25)
Hormonal stimulation in superovulation induces female mice to ovulate more oocytes than spontaneous ovulation. Because the superovulated oocytes contain a number of oocytes that normally regress before spontaneous ovulation or immature oocytes, the development of some embryos that derive from
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门