推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
60 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SLC22A11(55867)
免疫原
Synthetic peptide directed towards the C terminal region of human SLC22A11
应用
Anti-SLC22A11 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
生化/生理作用
SLC22A11 (Organic Anion Transporter 4, OAT4) is a membrane protein involved in sodium-dependent transport and excretion of organic anions. This protein is expressed mainly in placenta and in the kidney. A variant of the gene encoding OAT4 has been implicated in the development of a major gout subtype called renal underexcretion type gout.
序列
Synthetic peptide located within the following region: ASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Masayuki Sakiyama et al.
Drug metabolism and pharmacokinetics, 29(2), 208-210 (2013-09-13)
Gout, a common disease, is a consequence of hyperuricemia, and increases the risks of hypertension, cardiovascular diseases, cerebrovascular diseases and renal failure. Gout can be classified into 3 types: the renal underexcretion (RUE) type, renal overload type and combined type.
James E Shima et al.
American journal of physiology. Renal physiology, 299(4), F767-F775 (2010-07-30)
Apical reabsorption from the urine has been shown to be important for such processes as the maintenance of critical metabolites in the blood and the excretion of nephrotoxic compounds. The solute carrier (SLC) transporter OAT4 (SLC22A11) is expressed on the
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