AV43994
Anti-SLC22A11 (AB1) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-MGC34282, Anti-OAT4, Anti-Solute carrier family 22 (organic anion/urate transporter), member 11, Anti-hOAT4
产品名称
Anti-SLC22A11 (AB1) antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
60 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC22A11(55867)
Application
Anti-SLC22A11 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
SLC22A11 (Organic Anion Transporter 4, OAT4) is a membrane protein involved in sodium-dependent transport and excretion of organic anions. This protein is expressed mainly in placenta and in the kidney. A variant of the gene encoding OAT4 has been implicated in the development of a major gout subtype called renal underexcretion type gout.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide directed towards the C terminal region of human SLC22A11
Other Notes
Synthetic peptide located within the following region: ASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
常规特殊物品
此项目有
Masayuki Sakiyama et al.
Drug metabolism and pharmacokinetics, 29(2), 208-210 (2013-09-13)
Gout, a common disease, is a consequence of hyperuricemia, and increases the risks of hypertension, cardiovascular diseases, cerebrovascular diseases and renal failure. Gout can be classified into 3 types: the renal underexcretion (RUE) type, renal overload type and combined type.
James E Shima et al.
American journal of physiology. Renal physiology, 299(4), F767-F775 (2010-07-30)
Apical reabsorption from the urine has been shown to be important for such processes as the maintenance of critical metabolites in the blood and the excretion of nephrotoxic compounds. The solute carrier (SLC) transporter OAT4 (SLC22A11) is expressed on the
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