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Merck
CN
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安全信息

AV42656

Sigma-Aldrich

Anti-EGFL8 antibody produced in rabbit

IgG fraction of antiserum

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别名:
Anti-C6orf8, Anti-DAQB-143M3.8, Anti-EGF-like-domain, multiple 8, Anti-FLJ44493, Anti-MGC44938, Anti-MGC59719, Anti-NG3
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

32 kDa

种属反应性

human, mouse, rat, pig, horse, rabbit

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... EGFL8(80864)

一般描述

EGF-like-domain, multiple 8 (EGFL8), an EGFL7 paralog, is downregulated in metastatic colorectal cancers (CRC) making it a potential prognostic marker for poor prognosis in CRC and advanced gastric cancer.

特异性

Anti-EGFL8 polyclonal antibody reacts with pig, bovine, human, mouse, and rat EGF-like-domain, multiple 8 proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human EGFL8

应用

Anti-EGFL8 polyclonal antibody is used to tag EGF-like-domain, multiple 8 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of EGF-like-domain, multiple 8 protein as a potential prognostic marker for gastrointestinal cancers such as gastric cancer and colorectal cancer.

序列

Synthetic peptide located within the following region: QAGAWVRAVLPVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACS

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Ik-Jin Song et al.
International journal of molecular medicine, 36(2), 541-550 (2015-06-23)
Epidermal growth factor (EGF)-like (EGFL) domain, a common structural module in numerous secreted or transmembrane proteins, is generally involved in protein-protein interactions. To date, several EGFL proteins have been identified and characterized, but little is known about EGFL domain 8

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