生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
46 kDa
种属反应性
horse, bovine, rabbit, human, rat, guinea pig, mouse, dog
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TEAD1(7003)
一般描述
TEAD1是一种转录因子,可阻断人子宫蜕膜细胞中催乳素的表达。TEAD1突变与Sveinsson脉络膜视网膜萎缩有关。′
兔抗TEAD1抗体可识别猪、斑马鱼、人、小鼠、大鼠、牛和犬TEAD1。
兔抗TEAD1抗体可识别猪、斑马鱼、人、小鼠、大鼠、牛和犬TEAD1。
免疫原
对应人TEAD1 C末端区域的合成肽
应用
兔抗-TEAD1抗体适用于以0.25 μg/ml的浓度用于western blot应用,以16 μg/ml浓度进行免疫组化分析(IHC)。
生化/生理作用
TEAD1是一种转录增强子。可与骨骼肌特异性辅因子相互作用,促进骨骼肌基因表达。TEAD1基因突变是Sveinsson脉络膜视网膜萎缩的致病因。
序列
合成肽位于以下区域内: YMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK
外形
本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Human molecular genetics, 13(9), 975-981 (2004-03-16)
Sveinsson's chorioretinal atrophy (SCRA), also referred to as helicoid peripapillary chorioretinal degeneration or atrophia areata, is an autosomal dominant eye disease, characterized by symmetrical lesions radiating from the optic disc involving the retina and the choroid. Genome-wide linkage analysis mapped
JACC. Basic to translational science, 4(5), 611-622 (2019-11-27)
Patients with diabetes are more prone to developing heart failure in the presence of high blood pressure than those without diabetes. Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP
Molecular and cellular endocrinology, 295(1-2), 32-38 (2008-09-09)
Forced overexpression of TEAD1 in human uterine fibroblast (HUF) and human endometrial stromal cells markedly inhibited prolactin promoter activity in both cell types in a dose-dependent manner, with maximal inhibition of greater than 90%. Conversely, the knockdown of TEAD1 expression
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