生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
65 kDa
种属反应性
dog, human, rabbit, pig, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... USP39(10713)
免疫原
Synthetic peptide directed towards the N terminal region of human USP39
生化/生理作用
USP39 is a ubiquitin specific peptidase, a neuronal slicing factor expressed in the brain. It maintains embryonic pituitary homeostasis in Zebrafish by regulating expansion of all embryonic pituitary cell lineages. USP39 controls the levels of aurora B mRNA and is important to maintain the integrity of mitotic spindle checkpoint.
序列
Synthetic peptide located within the following region: MSGRSKRESRGSTRGKRESESRGSSGRVKRERDREREPEAASSRGSPVRV
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Yesenia Ríos et al.
PLoS genetics, 7(1), e1001271-e1001271 (2011-01-21)
Loss of retinoblastoma (Rb) tumor suppressor function is associated with human malignancies. Molecular and genetic mechanisms responsible for tumorigenic Rb downregulation are not fully defined. Through a forward genetic screen and positional cloning, we identified and characterized a zebrafish ubiquitin
Chiharu Kimura-Yoshida et al.
Communications biology, 5(1), 378-378 (2022-04-21)
Previously, we have shown that the translocation of Grainyhead-like 3 (GRHL3) transcription factor from the nucleus to the cytoplasm triggers the switch from canonical Wnt signaling for epidermal differentiation to non-canonical Wnt signaling for epithelial morphogenesis. However, the molecular mechanism
Renske J van Leuken et al.
Cell cycle (Georgetown, Tex.), 7(17), 2710-2719 (2008-08-30)
Accurate chromosome segregation relies on the mitotic spindle checkpoint. This checkpoint acts to restrict ubiquitin ligase activity of the Anaphase-promoting complex (APC/C) in mitosis until all chromosomes are bipolarly attached to the mitotic spindle. We performed a functional RNAi-based screen
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