推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
分子量
31 kDa
种属反应性
zebrafish, pig, canine, horse, guinea pig, rabbit, bovine, human, mouse, sheep, rat
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... VDAC1(7416)
一般描述
VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules.
免疫原
The immunogen for anti-VDAC1 antibody: synthetic peptide derected towards the C terminal of human VDAC1
应用
Muscle whole-cell extracts from mice were subjected to western blot analysis using rabbit anti-vdac as the primary antibody at a 1:2000 dilution.
序列
Synthetic peptide located within the following region: SAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
外形
Lyophilized from PBS buffer with 2% sucrose
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Sebastian Hiller et al.
Trends in biochemical sciences, 35(9), 514-521 (2010-08-17)
The most abundant protein of the mitochondrial outer membrane is the voltage-dependent anion channel (VDAC), which facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by interactions with other proteins and small molecules. VDAC has
Julio E Ayala et al.
Diabetes, 56(4), 1025-1033 (2007-01-19)
Stimulation of nitric oxide-cGMP signaling results in vascular relaxation and increased muscle glucose uptake. We show that chronically inhibiting cGMP hydrolysis with the phosphodiesterase-5 inhibitor sildenafil improves energy balance and enhances in vivo insulin action in a mouse model of
Mia Ydfors et al.
The Journal of physiology, 594(11), 3127-3140 (2015-12-04)
Mitochondrial respiratory sensitivity to ADP is thought to influence muscle fitness and is partly regulated by cytosolic-mitochondrial diffusion of ADP or phosphate shuttling via creatine/phosphocreatine (Cr/PCr) through mitochondrial creatine kinase (mtCK). Previous measurements of respiration in vitro with Cr (saturate
Claudio Asencio et al.
European journal of human genetics : EJHG, 24(3), 367-372 (2015-05-28)
Coenzyme Q10 (CoQ10) deficiency is associated to a variety of clinical phenotypes including neuromuscular and nephrotic disorders. We report two unrelated boys presenting encephalopathy, ataxia, and lactic acidosis, who died with necrotic lesions in different areas of brain. Levels of
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