推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
48 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TRIM31(11074)
一般描述
TRIM31是一种包含B-box、RING和卷曲螺旋三个锌结合结构域的蛋白质。TRIM31基因的改变与注意力缺陷/多动障碍（ADHD）有关，而蛋白质水平的变化与胃癌和非小细胞肺癌有关。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。
免疫原
靶向人TRIM31 N末端区域的合成肽
应用
兔抗TRIM31抗体适用于蛋白印迹（0.5 μg/ml）和IHC（4-8 μg/ml）分析。
生化/生理作用
TRIM31编码三重基序（TRIM）家族的成员。TRIM基序包括三个锌结合结构域，RING、B-box1和B-box2以及卷曲螺旋结构域。该蛋白质定位于细胞质和细胞核。
序列
位于以下区域内的合成肽： CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR
外形
本品为溶于1x PBS缓冲液的纯化抗体，含 0.09% (w/v) 叠氮化钠和2%蔗糖。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Hui Li et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5747-5752 (2014-02-26)
The present study aims to investigate expression pattern and biological roles of TRIM31 in human non-small cell lung cancer (NSCLC). We examined TRIM31 expression in 116 NSCLC tissues and 20 corresponding normal lung tissues by immumohistochemistry. We found TRIM31 downregulation
Thais S Rizzi et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156(2), 145-157 (2011-02-09)
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible
Shenglan Zeng et al.
Redox biology, 45, 102058-102058 (2021-07-05)
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not clarified. Here we demonstrated that TRIM31 was significantly downregulated in the ischemic brain and the
Takeyuki Sugiura
Cell biology international, 35(7), 657-661 (2011-01-15)
TRIM (tripartite motif) family proteins, comprising RING finger, B-box and coiled-coil domains, are involved in various cellular processes including tumour development and antiviral response. One of the family proteins, TRIM31, was originally identified as a gene induced by growth-suppressive retinoid.
Xiang He et al.
The EMBO journal, 38(14), e100978-e100978 (2019-07-16)
Viral infection triggers the formation of mitochondrial antiviral signaling protein (MAVS) aggregates, which potently promote immune signaling. Autophagy plays an important role in controlling MAVS-mediated antiviral signaling; however, the exact molecular mechanism underlying the targeted autophagic degradation of MAVS remains
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