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安全信息

AV34629

Sigma-Aldrich

Anti-LAS1L antibody produced in rabbit

affinity isolated antibody

别名:

Anti-FLJ12525, Anti-LAS1-like (S. cerevisiae), Anti-dJ475B7.2

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

分子量

83 kDa

种属反应性

human, bovine, horse

浓度

0.5 mg - 1 mg/mL

技术

western blot: suitable

NCBI登记号

UniProt登记号

储存温度

−20°C

基因信息

human ... LAS1L(81887)

一般描述

Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis. I has a molecular weight of 83 kDa.

免疫原

The immunogen for anti-LAS1L antibody: synthetic peptide derected towards the middle region of human LAS1L

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunoprecipitation (1 paper)

序列

Synthetic peptide located within the following region: SSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEE

外形

Lyophilized from PBS buffer with 2% sucrose

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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分析证书(COA)

Lot/Batch Number

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Christopher D Castle et al.
Molecular and cellular biology, 30(18), 4404-4414 (2010-07-22)
Ribosome biogenesis is a highly regulated process ensuring that cell growth (increase in biomass) is coordinated with cell proliferation. The formation of eukaryotic ribosomes is a multistep process initiated by the transcription and processing of rRNA in the nucleolus. Concomitant
Han Liao et al.
Molecular biology of the cell, 32(20), ar3-ar3 (2021-07-29)
Accumulating evidence indicates that increased ribosome biogenesis is a hallmark of cancer. It is well established that inhibition of any steps of ribosome biogenesis induces nucleolar stress characterized by p53 activation and subsequent cell cycle arrest and/or cell death. However

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