推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
24 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... IER2(9592)
一般描述
IER2 is an immediate early response gene that regulates FGF signaling and patterning in zebrafish. It is also known to enhance tumor cell invasion, and hence functions as a prognostic marker for colorectal cancer.
Rabbit Anti-IER2 antibody recognizes human IER2.
Rabbit Anti-IER2 antibody recognizes human IER2.
免疫原
Synthetic peptide directed towards the N terminal region of human IER2
应用
Rabbit Anti-IER2 antibody can be used for western blot applications at a concentration of 1 μg/ml. It can also be used for IHC applications at 4-8 μg/ml, using paraffin-embedded tissues.
序列
Synthetic peptide located within the following region: LYLSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEP
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Sung-Kook Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(7), 2230-2235 (2009-01-24)
Establishment of left-right asymmetry in vertebrates requires nodal, Wnt-PCP and FGF signaling and involves ciliogenesis in a laterality organ. Effector genes through which FGF signaling affects laterality have not been described. We isolated the zebrafish ier2 and fibp1 genes as
A Neeb et al.
Oncogene, 31(33), 3796-3806 (2011-11-29)
Here, we report unbiased screens for genes expressed in metastatic tumor cells that are associated with cell motility. These screens identified Ier2, an immediate early gene of unknown function, as potentially having a role in tumor cell motility and metastasis.
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