生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
44 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... KLF15(28999)
免疫原
针对人KLF15 N末端区域的合成肽
应用
兔抗KLF15抗体能够以1.0-2.0μg/ml的浓度用于蛋白质免疫印迹应用。它还能够以4-8μg/ml的浓度用于石蜡包埋组织的免疫组织化学应用。
生化/生理作用
KLF15是一种Cys2-His2锌指基因。它在肝脏、肾脏、心脏和骨骼肌中大量表达。
序列
合成肽位于以下区域内:DASSPCSCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGS
外形
本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Molecular medicine reports, 21(3), 1336-1345 (2020-01-11)
The aim of the present study was to investigate the protective effect of Kruppel‑like factor 15 (KLF15) overexpression on heart failure (HF) induced by left ventricular (LV) pressure overload in mice. Wild‑type (WT) mice and cardiac‑specific KLF15‑overexpressed transgenic (TG) mice
Journal of cellular and molecular medicine, 25(12), 5691-5706 (2021-05-06)
Mesangial cell (MC) proliferation is a key pathological feature in a number of common human renal diseases, including mesangial proliferative nephritis and diabetic nephropathies. Knowledge of MC responses to pathological stimuli is crucial to the understanding of these disease processes.
Clinical epigenetics, 13(1), 61-61 (2021-03-25)
Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the cardiac muscle, frequently caused by mutations in MYBPC3. However, little is known about the upstream pathways and key regulators causing the disease. Therefore, we employed a multi-omics approach to
International journal of molecular medicine, 42(3), 1593-1602 (2018-06-15)
Krüppel‑like factor 15 (KLF15), also known as kidney‑enriched transcription factor, is known to participate in podocyte differentiation. However, the role of KLF15 in chronic podocyte injury remains incompletely understood, particularly in proteinuric disease models. In the present study, the 5/6 nephrectomy
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