产品名称
抗-SIRT1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
82 kDa
species reactivity
rabbit, horse, guinea pig, rat, human, bovine, dog, mouse
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SIRT1(23411)
Application
兔多克隆抗SIRT1抗体用于标记sirtuin-1，以通过免疫细胞化学和免疫组化（IHC）技术进行检测和定量。它被用作探针来确定sirtuin-1在核转录控制和蛋白脱乙酰化水平上NAD（+）状态依赖性能量稳态中的存在和作用。
兔抗SIRT1抗体可在0.5 μg/ml浓度下用于蛋白质印迹应用。
Biochem/physiol Actions
SIRT1是sirtuin蛋白家族的成员，与酵母Sir2蛋白同源。sirtuin家族的成员以sirtuin核心域为特征，分为四类。人类sirtuins的功能尚未确定。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Sirtuin（沉默交配型信息调节2同源物）1（ 酿酒酵母）（SIRT1）是NAD（+）依赖性蛋白脱乙酰酶SIRT家族的成员，参与调节涉及能量代谢的基因的核转录。 SIRT1提供了细胞能量状态感知（NAD（+）状态）与能量稳态调节之间的联系。SIRT1参与代谢、细胞分化和衰老、应激反应和癌症的调节。
兔多克隆抗SIRT1抗体可与鸡，人，小鼠，大鼠，犬和猪的sirtuin-1酶反应。
Immunogen
靶向人SIRT1 N末端区域的合成肽
Other Notes
合成肽位于以下区域内： PETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKI
Physical form
本品为溶于1x PBS缓冲液的纯化抗体，含 0.09% (w/v) 叠氮化钠和2%蔗糖。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
常规特殊物品
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