推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
39 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CHX10(338917)
一般描述
CHX10 is a retinal homeo domain-containing protein. Mutations in CHX10 have been liked to human microphthalmia/anophthalmia.
Rabbit Anti-CHX10 antibody recognizes human, mouse, and canine CHX10.
Rabbit Anti-CHX10 antibody recognizes human, mouse, and canine CHX10.
免疫原
Synthetic peptide directed towards the C terminal region of human CHX10
应用
Rabbit Anti-CHX10 antibody can be used for western blot applications at a concentration of 0.5μg/ml.
生化/生理作用
Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina. The strong conservation in vertebrates of the CHX10 sequence, pattern of expression and loss-of-function phenotypes demonstrates the evolutionary importance of the genetic network through which this gene regulates eye development.
序列
Synthetic peptide located within the following region: ESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPKLDKM
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
E Ferda Percin et al.
Nature genetics, 25(4), 397-401 (2000-08-10)
Isolated human microphthalmia/anophthalmia, a cause of congenital blindness, is a clinically and genetically heterogeneous developmental disorder characterized by a small eye and other ocular abnormalities. Three microphthalmia/anophthalmia loci have been identified, and two others have been inferred by the co-segregation
Zihan Zhang et al.
The EMBO journal, 40(19), e107974-e107974 (2021-08-31)
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