产品名称
单克隆抗-NLRP3 小鼠抗, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0210, purified immunoglobulin, buffered aqueous glycerol solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
CL0210, monoclonal
product line
Prestige Antibodies® Powered by Atlas Antibodies
form
buffered aqueous glycerol solution
species reactivity
human
Quality Level
Gene Information
human ... NLRP3(114548)
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
concentration
1 mg/mL
technique(s)
immunoblotting: 1 μg/mL
immunofluorescence: 2-10 μg/mL (Fixation/Permeabilization: PFA/Triton X-100)
pH range
7.2-7.4
isotype
IgG1
Application
所有由 Atlas抗体®提供支持的 Prestige 抗体均由 Human Protein Atlas(HPA) 项目开发和验证。每种抗体都通过针对数百种正常和疾病组织的免疫组织化学进行测试。通过单击图像库链接,可以在人类蛋白质图谱(HPA)站点上查看这些图像。我们还提供Prestige Antibodies® 抗体的实验方案和其他有用信息。
Features and Benefits
Prestige Antibodies®是经过高度表征和广泛验证的抗体,同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige Antibodies®对其他蛋白质的独特性和低交叉反应性是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。每种Prestige 抗体都有相应的Prestige 抗原对照品,可在链接部分找到。
每种Prestige 抗体的检测方法如下:
每种Prestige 抗体的检测方法如下:
- 44种正常人体组织和20种最常见癌症组织的IHC组织阵列。
- 364个人重组蛋白片段的蛋白阵列。
Immunogen
NLR 家族,pyrin 结构域包含 3
Physical form
磷酸盐缓冲盐水,pH 7.2,含有40%甘油和0.02%叠氮化钠
Legal Information
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
Preparation Note
Upon arrival, mix gently and aliquot to avoid repeated freeze-thaw cycles
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Bing Zhou et al.
Oxidative medicine and cellular longevity, 2020, 6384803-6384803 (2020-06-09)
Vascular oxidative stress and inflammation play a major role in vascular diseases. This study was aimed at determining the protective roles of fibronectin type III domain-containing 5 (FNDC5) in angiotensin II- (Ang II-) induced vascular oxidative stress and inflammation and
Viviane Dias Faustino et al.
Bioscience reports, 38(4) (2018-06-20)
Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear mechanisms that may involve activation of innate immunity. We investigated whether prolonged exposure of tubular cells to high protein concentrations stimulates innate immunity, triggering progressive interstitial inflammation
Roberto Romero et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 79(6), e12440-e12440 (2016-03-10)
Inflammasomes are signaling platforms that, upon sensing pathogens and sterile stressors, mediate the release of mature forms of interleukin (IL)-1β and IL-18. The aims of this study were to determine (i) the expression of major inflammasome components in the chorioamniotic
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