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Merck
CN

A9517

Sigma-Aldrich

偶氮甲烷

13.4 M, >95% (GC)

别名:

AOM

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About This Item

线性分子式:
CH3N=N(→O)CH3
CAS号:
分子量:
74.08
MDL编号:
UNSPSC代码:
12352103

方案

>95% (GC)

浓度

13.4 M

沸点

97-99 °C (lit.)
97-99 °C (lit.)

溶解性

H2O: soluble
ethanol: soluble

密度

0.991 g/mL at 25 °C (lit.)
0.991 g/mL at 25 °C (lit.)

储存温度

−20°C

SMILES字符串

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

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生化/生理作用

诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成,并用于研究癌症进展和化学预防的机制。
Induces tumorigenesis in the colon of laboratory animals and is used to study the mechanism of cancer progression and chemoprevention.

象形图

Health hazardSkull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - Carc. 1B

储存分类代码

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Elham Rouhollahi et al.
Drug design, development and therapy, 9, 3911-3922 (2015-08-08)
Curcuma purpurascens BI. rhizome, a member of the Zingiberaceae family, is a popular spice in Indonesia that is traditionally used in assorted remedies. Dichloromethane extract of C. purpurascens BI. rhizome (DECPR) has previously been shown to have an apoptosis-inducing effect
E Fosslien
Annals of clinical and laboratory science, 30(1), 3-21 (2000-03-18)
Cyclooxygenase (COX)-2 levels are elevated in several types of human cancer tissues. Nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit both the COX-1 and COX-2 protein, the two enzymes that convert arachidonic acids to prostaglandins. Regular use of such NSAIDs significantly reduces
T Tanaka et al.
Cancer research, 61(6), 2424-2428 (2001-04-06)
The biological role of the peroxisome proliferator-activated receptors (PPARs) in various diseases, including inflammation and cancer, has been highlighted recently. Although PPARgamma ligands have been found to inhibit mammary carcinogenesis in rodents, the effects on colon tumorigenesis are controversial. In
C W Boone et al.
Cancer research, 50(1), 2-9 (1990-01-01)
A search of the literature using National Library of Medicine databases and individual cancer journal articles yielded over 500 compounds with published chemopreventive activity in animals. From these, an initial 16 agents or agent combinations have been evaluated in the

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