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Merck
CN

A9436

Sigma-Aldrich

N-Acetyl-β-Asp-Glu

≥98% (TLC), suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C11H16N2O8
CAS号:
分子量:
304.25
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

product name

N-Acetyl-β-Asp-Glu,

检测方案

≥98% (TLC)

形式

powder

技术

ligand binding assay: suitable

颜色

white to faint yellow

mp

115-116 °C

储存温度

−20°C

SMILES字符串

CC(=O)NC(CC(=O)NC(CCC(O)=O)C(O)=O)C(O)=O

InChI

1S/C11H16N2O8/c1-5(14)12-7(11(20)21)4-8(15)13-6(10(18)19)2-3-9(16)17/h6-7H,2-4H2,1H3,(H,12,14)(H,13,15)(H,16,17)(H,18,19)(H,20,21)

InChI key

GUCKKCMJTSNWCU-UHFFFAOYSA-N

Amino Acid Sequence

Nac-Asp-Glu

生化/生理作用

N-Acetyl-β-Asp-Glu (βNAAG) is used as a substrate/inhibitor to identify and characterize glutamate carboxypeptidase(s). βNAAG is often used together witn N-Acetyl-Asp-Glu (NAAG), a neuropeptide, to differentiate the activity of glutamate carboxypeptidase activity and function in vivo.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

分析证书(COA)

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Artem I Malomouzh et al.
Journal of neurochemistry, 94(1), 257-267 (2005-06-15)
N-Acetylaspartylglutamate (NAAG), known to be present in rat motor neurons, may participate in neuronal modulation of non-quantal secretion of acetylcholine (ACh) from motor nerve terminals. Non-quantal release of ACh was estimated by the amplitude of the endplate membrane hyperpolarization (H-effect)
François Collard et al.
The Journal of biological chemistry, 286(44), 38220-38230 (2011-09-13)
β-Citrylglutamate (BCG), a compound present in adult testis and in the CNS during the pre- and perinatal periods is synthesized by an intracellular enzyme encoded by the RIMKLB gene and hydrolyzed by an as yet unidentified ectoenzyme. To identify β-citrylglutamate
Seiichi Sakatani et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(43), 10928-10936 (2008-10-24)
S100B is the principal calcium-binding protein of astrocytes and known to be secreted to extracellular space. Although secreted S100B has been reported to promote neurite extension and cell survival via its receptor [receptor for advanced glycation end products (RAGE)], effects

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