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生物来源
bovine kidney
质量水平
描述
Minimum 50 ng protein/vial by Bradford
表单
aqueous solution
比活
~17,000 units/mg protein
分子量
36 kDa
运输
dry ice
储存温度
−70°C
生化/生理作用
This enzyme phosphorylates and inactivates protein phosphatase 2A. The funtion appears to be related to the catalytic domain of p21-activated p65(PAK) protein kinase which is produced in apoptotic cells. AK is also involved in cytoskeleton organization and other signal transduction processes.
单位定义
One unit is the amount of enzyme that will incorporate 1 nmole of phosphoryl groups using myelin basic protein as a substrate per minute at pH 7 at 30 deg C.
外形
50 ng per vial in 10 μl of 50 mM Tris-HCl, pH 7.0, containing 14 mM β-Mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, 65% ethyleneglycol, and 0.1% Brij® 35.
法律信息
Brij is a registered trademark of Croda International PLC
储存分类代码
10 - Combustible liquids
法规信息
新产品
Jinlan Luo et al.
The Journal of biological chemistry, 296, 100667-100667 (2021-04-18)
The epoxyeicosatrienoic acid (EET) exerts beneficial effects on insulin resistance and/or hypertension. EETs could be readily converted to less biological active diols by soluble epoxide hydrolase (sEH). However, whether sEH inhibition can ameliorate the comorbidities of insulin resistance and hypertension
Yadong Fan et al.
Frontiers in immunology, 13, 959495-959495 (2022-08-16)
Macrophages are involved in hepatocyte steatosis and necroinflammation and play an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Impaired autophagy function (decreased autophagy or blocked autophagic flow) leads to cell damage and death and promotes NAFLD
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