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Merck
CN

A8763

Sigma-Aldrich

白蛋白 来源于人类血清

lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis)

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别名:
HSA
CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352202
eCl@ss:
42010201
NACRES:
NA.25

生物来源

human

质量水平

检测方案

≥99% (agarose gel electrophoresis)

形式

lyophilized powder

分子量

monomer calculated mol wt 66478 Da

技术

ELISA: suitable
tissue culture: suitable
western blot: suitable

杂质

HIV I and HIVII, HCV and HBsAg, tested negative

溶解性

H2O: soluble 20 mg/mL

UniProt登记号

储存温度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

基因信息

human ... ALB(213)

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一般描述

白蛋白是血浆中最丰富的蛋白质。肝脏产生人白蛋白。

应用

白蛋白用于测试其对头孢托仑对耐青霉素的肺炎链球菌体外杀菌活性的影响。它已在临床上用于严重和经常危及生命的情况,例如由于外伤、烧伤和手术引起的休克和失血。
白蛋白用于研究白蛋白诱导的近端小管细胞凋亡。 它还用于细胞粘连分子和表面治疗研究。

生化/生理作用

血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。

其他说明

更多信息参见人血清白蛋白

免责声明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves

法规信息

常规特殊物品

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Tamás Pivarcsik et al.
Pharmaceuticals (Basel, Switzerland), 14(6) (2021-06-03)
In this work, the various biological activities of eight organoruthenium(II) complexes were evaluated to reveal correlations with their stability and reactivity in aqueous media. Complexes with general formula [Ru(η6-p-cymene)(X,Y)(Z)] were prepared, where (X,Y) represents either an O,O-ligand (β-diketone), N,O-ligand (8-hydroxyquinoline)
H K Parmentier et al.
Poultry science, 88(3), 536-542 (2009-02-13)
To mimic airborne immune challenges, layer hens were intratracheally and concurrently challenged with various doses of the protein antigen human serum albumin (HuSA) and the pathogen-associated molecular pattern lipopolysaccharide (LPS) at 7 and 13 wk of age. All groups received
Nóra V May et al.
Molecules (Basel, Switzerland), 26(9) (2021-06-03)
Copper(II) complexes of thiosemicarbazones (TSCs) often exhibit anticancer properties, and their pharmacokinetic behavior can be affected by their interaction with blood transport proteins. Interaction of copper(II) complexes of an {N,N,S} donor α-N-pyridyl TSC (Triapine) and an {O,N,S} donor 2-hydroxybenzaldehyde TSC
Nitin Agrawal et al.
Lab on a chip, 8(12), 2054-2061 (2008-11-22)
Neutrophil directional migration in response to chemical gradients, also known as chemotaxis, is one of the key phenomena in the immune responses against bacterial infection. To better study neutrophils chemotaxis, several in vitro assays have been developed that replicate chemotactic
Zonghua Liu et al.
Biomaterials, 31(12), 3364-3373 (2010-02-04)
Hydrophobically derivatized hyperbranched polyglycerol (HPG)-polyethylene glycol (PEG) polymers bearing stearoyl chains (HPG-C18-PEG) were originally developed as human serum albumin substitutes and further as a unimolecular drug delivery system. In view of these in vivo applications and the potential for membrane

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