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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
fractionated antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
技术
capture ELISA: 1:4,000 using aflatoxin B1-BSA
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
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一般描述
该抗体可以与B1黄曲霉毒素反应，还能识别黄曲霉毒素G1、B2和KLH蛋白。尚未观察到黄曲霉毒素与B2a、G2、G2a、M1存在交叉反应。
霉菌毒素是一组化学性质多样的次级真菌代谢产物，当摄入含有这些化合物的食物和饲料时，它们可在人和动物体内引起多种毒性反应。快速定量霉菌毒素污染的水平有助于减少这些毒素的暴露。
黄曲霉毒素具有高度致癌性。
黄曲霉毒素是由曲霉菌产生的剧毒性真菌毒素。黄曲霉毒素通常存在于各种谷物和花生酱中。
黄曲霉素B1是这一类中最为常见且重要的成员，其他还包括B2、B2a、G1、G2a、M1、M2、P1、Q1、黄曲霉毒醇I（天然异构体）、黄曲霉毒醇II（非天然异构体）、四氢脱氧黄曲霉毒素B1和不稳定的反应性B1(8,9)-环氧化物。
特异性
该产品的灵敏度范围是 0.005-20 ng/ml黄曲霉毒素B1。
免疫原
黄曲霉毒素 B1-KLH.
应用
兔抗黄曲霉毒素B1抗体已用于开发电化学免疫传感器。该抗体还被用于设计新型夹心免疫测定。本品还能够以1:1,000的稀释度用于捕获ELISA。
生化/生理作用
黄曲霉素B1及其代谢物可成为强力致癌物、诱变剂和致畸剂。黄曲霉素与人类肝细胞癌、黄曲霉素中毒、Reys′综合征、慢性肝炎和畜牧业感染死亡率升高有关。
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Jeong Moon et al.
Sensors (Basel, Switzerland), 18(2) (2018-02-22)
Aflatoxins (AFs) are highly toxic compounds that can cause both acute and chronic toxicity in humans. Aflatoxin B1 (AFB1) is considered the most toxic of AFs. Therefore, the rapid and on-site detection of AFB1 is critical for food safety management.
C G Caratsch et al.
Neuroscience letters, 111(3), 344-350 (1990-04-06)
The effects of calcitonin gene-related peptide (CGRP) on synaptic mechanisms were studied at the frog neuromuscular junction by using classical electrophysiological techniques. CGRP reduced the quantal content of evoked neurotransmitter release, as well as the sensitivity of postsynaptic nicotinic acetylcholine
Joseph H O Owino et al.
Analytical and bioanalytical chemistry, 388(5-6), 1069-1074 (2007-06-15)
Aflatoxins are a group of mycotoxins that have deleterious effects on humans and are produced during fungal infection of plants or plant products. An electrochemical immunosensor for the determination of aflatoxin B(1) (AFB(1)) was developed with AFB(1)antibody (AFB(1)-Ab) immobilized on
Gilcelia J L S Barbieri et al.
Biotechnology progress, 39(3), e3334-e3334 (2023-02-17)
This article developed a novel electrochemical immunosensor for the specific detection of aflatoxin B1 (AFB1). Amino-functionalized iron oxide nanoparticles (Fe3 O4 -NH2 ) were synthesized. Fe3 O4 -NH2 were chemically bound on self-assembly monolayers (SAMs) of mercaptobenzoic acid (MBA). Finally
Wenqiang Lai et al.
Biosensors & bioelectronics, 89(Pt 1), 645-651 (2016-01-05)
A new colorimetric immunosensing platform accompanying enzyme cascade amplification strategy was fabricated for quantitative screening of small-molecular mycotoxins (aflatoxin B1, AFB1 used in this case) coupling with enzyme-controlled dissolution of MnO2 nanoflakes. The visual colored assay was executed by high-efficient
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